MIS/AMH Antibody [Alexa Fluor® 488]

• Reactivity: Hu
• Applications: WB, IHC
• Clonality: Polyclonal
• Host: Goat
• Conjugate: Alexa Fluor 488

MIS/AMH Antibody [Alexa Fluor® 488] Summary

• Immunogen: Mouse myeloma cell line NS0-derived recombinant human MIS/AMH Propeptide
  Leu19-Gln450
  Accession # P03971
• Specificity: Detects human MIS/AMH Propeptide in direct ELISAs and Western blots. In direct ELISAs, less than 1% cross-reactivity with mature recombinant human MIS is observed.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Goat
• Purity Statement: Antigen Affinity-purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry
  • Western Blot

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied
• Buffer: Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for MIS/AMH Antibody [Alexa Fluor® 488]

• AMH
• MIF
• MIS
• Muellerian hormone
• muellerian-inhibiting factor
• muellerian-inhibiting substance
• Mullerian hormone
• Mullerian inhibiting factor
• Mullerian inhibiting substance

Background

MIS, also known as anti-Mullerian Hormone (AMH), belongs to the TGF-beta superfamily. It is synthesized as a 140 kDa homodimeric glycoprotein that undergoes proteolytic cleavage into the bioactive homodimeric 26 kDa carboxy-terminus and the 110 kDa dimeric amino-terminus. After cleavage, the amino-terminal propeptide remains non-covalently associated with the bioactive carboxy-terminal active protein. The amino acid sequence of human and mouse MIS propeptides are 67% identical.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.