MGP Antibody

Images

 
Immunohistochemistry-Paraffin: MGP Antibody [NBP1-86465] - Staining of human soft tissue shows strong cytoplasmic positivity in chondrocytes.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications IHC, IHC-P
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated

Order Details

MGP Antibody Summary

Immunogen
This antibody was developed against Recombinant Protein corresponding to amino acids: ESMESYELNPFINRRNANTFISPQQRWRAKVQERIRERSKPVHELNREACDDYRLCERYAMVYGYNAAYNRYFR
Specificity
Specificity of human MGP antibody verified on a Protein Array containing target protein plus 383 other non-specific proteins.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
MGP
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunohistochemistry 1:200 - 1:500
  • Immunohistochemistry-Paraffin 1:200 - 1:500
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.
Control Peptide
MGP Protein (NBP1-86465PEP)
Publications
Read Publication using NBP1-86465.

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: Mouse (84%), Rat (81%). Reactivity reported in scientific literature (PMID: 23284864)

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.2) and 40% Glycerol
Preservative
0.02% Sodium Azide
Purity
Immunogen affinity purified

Alternate Names for MGP Antibody

  • Cell growth-inhibiting gene 36 protein
  • matrix Gla protein
  • MGLAP
  • NTI

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for MGP Antibody (NBP1-86465)(1)

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Product General Protocols

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FAQs for MGP Antibody (NBP1-86465). (Showing 1 - 1 of 1 FAQ).

  1. I am about to study the expression of MGP in valvular tissue. This protein is a vitamin K dependent BMP2 inhibitor and protect from calcification. The protein is gamma-carboxylated by vitamin K and the literature reports ELISA assays on dp-cMGP (carboxylated) and dp-ucMGP (uncarboxylated). Do you know which form (carb or uncarb) is recognized by this antibody? Also, are you aware of the availability of an antibody to detect the uncarboxylated form in IHC-P?
    • Our MGP antibody with catalogue number NBP1-86465 was generated against a recombinant protein corresponding to amino acids 24-97 of the human protein. Unfortunately we do not have any testing data which shows whether this antibody is specific to a carboxylated or decarboxylated form of the protein. I am sorry for any inconvenience.

Secondary Antibodies

 

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Calculators

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Bioinformatics

Gene Symbol MGP