mGluR1 Antibody (5E12D8) - BSA Free

Western Blot: mGluR1 Antibody (5E12D8) [NBP2-61827] - Analysis using GRM1 mAb against human GRM1 (AA: 387-486) recombinant protein. (Expected MW is 37.1 kDa)

Western Blot: mGluR1 Antibody (5E12D8) [NBP2-61827] - Analysis using GRM1 mAb against HEK293 (1) and GRM1 (AA: 387-486)-hIgGFc transfected HEK293 (2) cell lysate.

ELISA: mGluR1 Antibody (5E12D8) [NBP2-61827] - Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)

• Reactivity: Hu
• Applications: WB, ELISA
• Clone: 5E12D8
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Unconjugated
• Format: BSA Free
• Concentration: 1 mg/ml

mGluR1 Antibody (5E12D8) - BSA Free Summary

• Immunogen: Purified recombinant fragment of human mGluR1 (AA: extra 387-486) expressed in E. Coli.
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Gene: GRM1
• Purity: Protein G purified

Applications/Dilutions

• Dilutions:
  • ELISA 1:100-1:2000
  • Western Blot 1:100-1:2000
• Theoretical MW: 132.4 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS
• Preservative: 0.05% Sodium Azide
• Concentration: 1 mg/ml
• Purity: Protein G purified

Alternate Names for mGluR1 Antibody (5E12D8) - BSA Free

• glutamate receptor, metabotropic 1
• GPRC1A
• GRM1
• GRM1A
• metabotropic glutamate receptor 1
• mGluR1
• MGLUR1A
• MGLUR1GPRC1AmGlu1

Background

This gene encodes a metabotropic glutamate receptor that functions by activating phospholipase C. L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The canonical alpha isoform of the encoded protein is a disulfide-linked homodimer whose activity is mediated by a G-protein-coupled phosphatidylinositol-calcium second messenger system. This gene may be associated with many disease states, including schizophrenia, bipolar disorder, depression, and breast cancer. Alternative splicing results in multiple transcript variants encoding different isoforms.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: GRM1