HOMER1 Antibody

Images

 
Western Blot: HOMER1 Antibody [NBP1-44999] - Analysis of HOMER1 on human brain lysate.
Immunocytochemistry/ Immunofluorescence: HOMER1 Antibody [NBP1-44999] - Detection of HOMER1 (Green) in Hela cells using NBP1-44999. Nuclei (Blue) are counterstained using Hoechst 33258.
Western Blot: HOMER1 Antibody [NBP1-44999] - Analysis of HOMER1 on mouse brain lysate.

Product Details

Summary
Reactivity Hu, Mu, Rt, Bv, XpSpecies Glossary
Applications WB, ICC/IF
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated

Order Details

HOMER1 Antibody Summary

Immunogen
N-terminal partial recombinant human HOMER protein expressed in E. coli. [Swiss-Prot# Q86YM7]
Localization
Cytoplasm By similarity. Cell junction synapse postsynaptic cell membrane postsynaptic density. Cell junction synapse. Note: Postsynaptic density of neuronal cells. Isoform 1 inhibits surface expression of GRM5 causing it to be retained in the end
Predicted Species
Rat (99%), Xenopus (96%), Bovine (98%). Backed by our 100% Guarantee.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
HOMER1
Purity
Unpurified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1:1000
  • Immunocytochemistry/Immunofluorescence 1:100
Application Notes
This HOMER1 antibody is useful in Immunocytochemistry/Immunofluorescence and Western blot, where a band at ~40 kDa is observed. The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Theoretical MW
40 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Control
Mouse Brain Whole Tissue Lysate (Adult Whole Normal)
Human Brain Whole Tissue Lysate (Adult Whole Normal)
Publications
Read Publications using
NBP1-44999 in the following applications:

  • WB
    2 publications

Reactivity Notes

Reacts with human and mouse. Immunogen sequence has 99% identity to rat, 98% to bovine, 96% to Xenopus and 74% to zebrafish.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
Whole antisera
Preservative
0.1% Sodium Azide
Purity
Unpurified

Alternate Names for HOMER1 Antibody

  • homer homolog 1 (Drosophila)
  • HOMER
  • HOMER1
  • homer-1
  • HOMER1A
  • HOMER1B
  • HOMER-1B
  • HOMER1C
  • SYN47
  • SYN47neuronal immediate early gene, 1
  • Ves-1

Background

Homer 1 (Homer protein homolog 1) belongs to the Homer family of proteins that regulate signal transduction through, and the trafficking of, glutamate receptors, as well as maintain and regulate extracellular glutamate levels in corticolimbic brain regions. The Homer 1 is enriched at excitatory synapses and binds group 1 metabotropic glutamate receptors (mGluRs).

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for HOMER1 Antibody (NBP1-44999)(3)

Reviews for HOMER1 Antibody (NBP1-44999) (0)

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Product General Protocols

View specific protocols for HOMER1 Antibody (NBP1-44999): Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

Video Protocols

WB Video Protocol
ICC/IF Video Protocol

FAQs for HOMER1 Antibody (NBP1-44999). (Showing 1 - 1 of 1 FAQs).

  1. Do you by chance sell the N-terminal recombinant protein that was used to generate this antibody? If so could you please confirm the catalog number?
    • Unfortunately we do not have this N-Term recombinant protein available for sale. In most cases when the immunogen is available it will be listed under the same cat# but with a PEP after (NBP1-44999PEP). In some cases we are able to get it, but those are rare, so it doesn't hurt to ask.

Control Lysate(s)

Secondary Antibodies

 

Isotype Controls

Other Available Formats

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Bioinformatics

Gene Symbol HOMER1
Entrez
Uniprot