mGluR1 Products

Description

L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors, that have been divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. The Glutamate Receptor, Metabotropic, 1, (mGluR1 alpha) activates phospholipase C and participates in the central action of glutamate in the central nervous system, such as long-term potentiation in the hippocampus and long-term depression in the cerebellum.

Bioinformatics

Entrez	14816 Mouse 24414 Rat 2911 Human
Uniprot	NP_000829 Human NP_000829 Human Q13255 Human Q13255 Human
Product By Gene ID	2911
Alternate Names	glutamate receptor, metabotropic 1 GRM1A metabotropic glutamate receptor 1 mGluR1 MGLUR1A MGLUR1GPRC1AmGlu1

Research Areas for mGluR1

Find related products by research area and learn more about each of the different research areas below.

GPCR
Metabotropic Glutamate Receptors
Neuronal Cell Markers
Neuroscience
Neurotransmission
Vision