MCTS1 Antibody


Genetic Strategies: Western Blot: MCTS1 Antibody [NBP2-17242] - Non-transfected (-) and transfected (+) MDA-MB-231 whole cell extracts (30 ug) were separated by 12% SDS-PAGE, and the membrane was blotted with more
Immunohistochemistry-Paraffin: MCTS1 Antibody [NBP2-17242] - Paraffin-embedded rat spleen. MCTS1 antibody [N1C3] diluted at 1:500.
Western Blot: MCT1 Antibody [NBP2-17242] - Sample (30 ug of whole cell lysate) A: Jurkat 12% SDS PAGE gel, diluted at 1:1000.
Immunohistochemistry-Paraffin: MCTS1 Antibody [NBP2-17242] - Paraffin-embedded mouse lung. MCTS1 antibody [N1C3] diluted at 1:500.

Product Details

Reactivity Hu, Mu, Rt, Bv, Ch, Xp, ZeSpecies Glossary
Applications WB, IHC, IHC-P
Validated by:

Genetic Strategies


Order Details

MCTS1 Antibody Summary

Recombinant protein encompassing a sequence within the center region of human MCTS1. The exact sequence is proprietary.
Predicted Species
Chicken (97%), Xenopus (97%), Zebrafish (95%), Bovine (100%). Backed by our 100% Guarantee.
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.


  • Western Blot 1:500-1:3000
  • Immunohistochemistry 1:100-1:1000
  • Immunohistochemistry-Paraffin 1:100-1:1000
Theoretical MW
21 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Reactivity Notes

Xenopus laevis (97%).

Packaging, Storage & Formulations

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
PBS (pH 7.0), 1.0% BSA and 20% Glycerol
0.01% Thimerosal
Immunogen affinity purified

Alternate Names for MCTS1 Antibody

  • HHF7
  • malignant T cell amplified sequence 1
  • Malignant T-Cell-Amplified Sequence 1
  • MCT1
  • MCT-1
  • Multiple Copies T-Cell Malignancies
  • SLC16A1


Anti-oncogene that play a role in cell cycle regulation; decreases cell doubling time and anchorage-dependent growth; shortens the duration of G1 transit time and G1/S transition. When constituvely expressed, increases CDK4 and CDK6 kinases activity and CCND1/cyclin D1 protein level, as well as G1 cyclin/CDK complex formation. Plays a role as translation enhancer; Recruits the density-regulated protein/DENR and binds to the cap complex of the 5'-terminus of mRNAs, subsequently altering the mRNA translation profile; Up-regulates protein levels of BCL2L2, TFDP1, MRE11A, CCND1 and E2F1, while mRNA levels remains constant. Hyperactivates DNA damage signaling pathway; increased gamma-irradiation-induced phosphorylation of histone H2AX, and induces damage foci formation. Increases the overall number of chromosomal abnormalities such as larger chromosomes formation and multiples chromosomal fusions when over-expressed in gamma-irradiated cells. May play a role in promoting lymphoid tumor development: lymphoid cell lines over-expressing MCTS1 exhibit increased growth rates and display increased protection against apoptosis. May contribute to the pathogenesis and progression of breast cancer via promotion of angiogenesis through the decline of inhibitory THBS1/thrombospondin-1, and inhibition of apoptosis. Involved in the process of proteosome degradation to down-regulate Tumor suppressor p53/TP53 in breast cancer cell; Positively regulates phosphorylation of MAPK1 and MAPK3.


This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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FAQs for MCTS1 Antibody (NBP2-17242). (Showing 1 - 1 of 1 FAQ).

  1. I am looking for MCT1 primaries in a chicken host.
    • We don't have a chicken host antibody at this time, but we do have these MCT1 antibodies available. We will guarantee all species and applications listed on the datasheet, and if you have any additional questions or concerns on any of these products let me know and I would be happy to help,

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Gene Symbol MCTS1