MCTS1 Antibody

Images

 
Western Blot: MCTS1 Antibody [NBP2-17242] - Non-transfected (-) and transfected (+) MDA-MB-231 whole cell extracts (30 ug) were separated by 12% SDS-PAGE, and the membrane was blotted with MCTS1 antibody [N1C3] diluted ...read more
Immunohistochemistry-Paraffin: MCTS1 Antibody [NBP2-17242] - Paraffin-embedded rat spleen. MCTS1 antibody [N1C3] diluted at 1:500.
Western Blot: MCT1 Antibody [NBP2-17242] - Sample (30 ug of whole cell lysate) A: Jurkat 12% SDS PAGE gel, diluted at 1:1000.
Immunohistochemistry-Paraffin: MCTS1 Antibody [NBP2-17242] - Paraffin-embedded mouse lung. MCTS1 antibody [N1C3] diluted at 1:500.

Product Details

Summary
Reactivity Hu, Mu, Rt, Bv, Ch, Xp, ZeSpecies Glossary
Applications WB, IHC, IHC-P
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
1 mg/ml

Order Details

MCTS1 Antibody Summary

Immunogen
Recombinant protein encompassing a sequence within the center region of human MCTS1. The exact sequence is proprietary.
Predicted Species
Bovine (100%), Chicken (97%), Xenopus (97%), Zebrafish (95%). Backed by our 100% Guarantee.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
MCTS1
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1:500-1:3000
  • Immunohistochemistry 1:100-1:1000
  • Immunohistochemistry-Paraffin 1:10 - 1:500
Application Notes
The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Theoretical MW
21 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Reactivity Notes

Xenopus laevis (97%).

Packaging, Storage & Formulations

Storage
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.0), 1.0% BSA and 20% Glycerol
Preservative
0.01% Thimerosal
Concentration
1 mg/ml
Purity
Immunogen affinity purified

Alternate Names for MCTS1 Antibody

  • HHF7
  • malignant T cell amplified sequence 1
  • Malignant T-Cell-Amplified Sequence 1
  • MCT1
  • MCT-1
  • Multiple Copies T-Cell Malignancies
  • SLC16A1

Background

Anti-oncogene that play a role in cell cycle regulation; decreases cell doubling time and anchorage-dependent growth; shortens the duration of G1 transit time and G1/S transition. When constituvely expressed, increases CDK4 and CDK6 kinases activity and CCND1/cyclin D1 protein level, as well as G1 cyclin/CDK complex formation. Plays a role as translation enhancer; Recruits the density-regulated protein/DENR and binds to the cap complex of the 5'-terminus of mRNAs, subsequently altering the mRNA translation profile; Up-regulates protein levels of BCL2L2, TFDP1, MRE11A, CCND1 and E2F1, while mRNA levels remains constant. Hyperactivates DNA damage signaling pathway; increased gamma-irradiation-induced phosphorylation of histone H2AX, and induces damage foci formation. Increases the overall number of chromosomal abnormalities such as larger chromosomes formation and multiples chromosomal fusions when over-expressed in gamma-irradiated cells. May play a role in promoting lymphoid tumor development: lymphoid cell lines over-expressing MCTS1 exhibit increased growth rates and display increased protection against apoptosis. May contribute to the pathogenesis and progression of breast cancer via promotion of angiogenesis through the decline of inhibitory THBS1/thrombospondin-1, and inhibition of apoptosis. Involved in the process of proteosome degradation to down-regulate Tumor suppressor p53/TP53 in breast cancer cell; Positively regulates phosphorylation of MAPK1 and MAPK3.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Customers Who Viewed This Item Also Viewed...

NBP1-59656
Species: Hu, Mu
Applications: WB, ICC/IF, IHC, IHC-P
NBP2-13315
Species: Hu
Applications: IHC, IHC-P
NBP1-81251
Species: Hu
Applications: WB, Simple Western, ICC/IF, IHC, IHC-Fr, IHC-P
NBP1-87846
Species: Hu
Applications: WB, IHC, IHC-P
NBP1-83936
Species: Hu
Applications: WB, IHC, IHC-P
AF3998
Species: Hu
Applications: WB
AF972
Species: Hu
Applications: WB, Simple Western, IHC
NB110-39113
Species: Hu, Mu, Rt
Applications: WB, ChIP, Flow, ICC/IF, IHC, IHC-Fr, IHC-P
NBP1-59885
Species: Hu, Mu
Applications: WB, IHC, IHC-P
NBP2-43648
Species: Hu, Mu, Rt, Ze
Applications: WB, ICC/IF, IHC, IHC-P
NBP2-32109
Species: Hu, Mu
Applications: WB, IP
NB600-1036
Species: Hu, Mu, Rt, Ca, Pm
Applications: WB, B/N, ICC/IF, IHC, IHC-P, IP
MAB8398
Species: Hu
Applications: Flow, CyTOF-ready
NBP1-49533
Species: Hu, Mu, Rt
Applications: WB, Flow, ICC/IF, IHC, IHC-P
NB100-524
Species: Hu, Mu
Applications: WB, Flow, ICC/IF, IHC, IHC-P, IP, Flow-IC
NBP1-84550
Species: Hu
Applications: WB, ICC/IF, IHC, IHC-P
NBP2-22124
Species: Hu, Mu, Pm
Applications: WB, ELISA, Flow, ICC/IF, IHC, IHC-P
NBP1-48336
Species: Hu, Mu
Applications: WB, Simple Western, ICC/IF, IHC, IHC-Fr, IHC-P

Publications for MCTS1 Antibody (NBP2-17242) (0)

There are no publications for MCTS1 Antibody (NBP2-17242).
By submitting your publication information earn gift cards and discounts for future purchases.

Reviews for MCTS1 Antibody (NBP2-17242) (0)

There are no reviews for MCTS1 Antibody (NBP2-17242). By submitting a review earn points towards our Rewards Program.
  • 250 points for product review
  • 500 additional points for an image with your product review
  • Double points (500) if you are the first to review this product
  • Double points (1000) if you are the first to review this product with an image

Product General Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

Video Protocols

WB Video Protocol

FAQs for MCTS1 Antibody (NBP2-17242). (Showing 1 - 1 of 1 FAQ).

  1. I am looking for MCT1 primaries in a chicken host.
    • We don't have a chicken host antibody at this time, but we do have these MCT1 antibodies available. We will guarantee all species and applications listed on the datasheet, and if you have any additional questions or concerns on any of these products let me know and I would be happy to help, technical@novusbio.com.

Secondary Antibodies

 

Isotype Controls

Additional MCTS1 Antibody Products

Related Products by Gene

Bioinformatics Tool for MCTS1 Antibody (NBP2-17242)

Discover related pathways, diseases and genes to MCTS1 Antibody (NBP2-17242). Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
Visit Tool

Diseases for MCTS1 Antibody (NBP2-17242)

Discover more about diseases related to MCTS1 Antibody (NBP2-17242).
 

Pathways for MCTS1 Antibody (NBP2-17242)

View related products by pathway.

PTMs for MCTS1 Antibody (NBP2-17242)

Learn more about PTMs related to MCTS1 Antibody (NBP2-17242).

Blogs on MCTS1

There are no specific blogs for MCTS1, but you can read our latest blog posts.

Contact Information

Product PDFs

Calculators

Concentration Calculator

The concentration calculator allows you to quickly calculate the volume, mass or concentration of your vial. Simply enter your mass, volume, or concentration values for your reagent and the calculator will determine the rest.

=
÷

Review this Product

Be the first to review our MCTS1 Antibody and receive a gift card or discount.

Bioinformatics

Gene Symbol MCTS1
Entrez
Uniprot

Customers Who Bought This Also Bought