MBL Antibody

Western Blot: MBL Antibody [NB100-1502] - Staining of Human Heart (A) and Liver (B) lysate (35 ug protein in RIPA buffer). Antibody at 1 ug/mL. Detected by chemiluminescence.

• Reactivity: Hu
• Applications: WB, ELISA
• Clonality: Polyclonal
• Host: Goat
• Conjugate: Unconjugated
• Concentration: 0.5 mg/ml

MBL Antibody Summary

• Description: Novus Biologicals Goat MBL Antibody (NB100-1502) is a polyclonal antibody validated for use in IHC, WB, ELISA and ICC/IF. Anti-MBL Antibody: Cited in 3 publications. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: Peptide with sequence STSHLAVCEFPI corresponding to C-Terminus according to NP_000233.1.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Goat
• Gene: MBL2
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Peptide ELISA Detection limit 1:2000
  • Western Blot 1 - 3 ug/mL
• Application Notes: Use in ICC/IF reported in scientific literature (PMID: 33158953). Use in Immunohistochemistry-Frozen reported in scientific literature (PMID: 31900334). Data was not shown by authors in either.
• Control:

  MBL Overexpression Lysate

• Control Peptide:

  MBL Peptide (NB100-1502PEP)

Reactivity Notes

Use in Mouse reported in scientific literature (PMID:33158953).

Packaging, Storage & Formulations

• Storage: Store at -20C. Avoid freeze-thaw cycles.
• Buffer: Tris saline (20 mM Tris pH 7.3, 150 mM NaCl), 0.5% BSA
• Preservative: 0.02% Sodium Azide
• Concentration: 0.5 mg/ml
• Purity: Immunogen affinity purified

Alternate Names for MBL Antibody

• COLEC1
• COLEC1collectin-1
• Collectin-1
• HSMBPC
• Mannan-binding protein
• mannose-binding lectin (protein C) 2, soluble (opsonic defect)
• mannose-binding lectin (protein C) 2, soluble
• Mannose-binding lectin
• mannose-binding protein C
• MBL
• MBL2
• MBL2D
• MBLmannan-binding lectin
• MBP
• MBP1
• MBP1mannose-binding lectin 2, soluble (opsonic defect)
• MBP-C
• MGC116832
• MGC116833

Background

Mannan-binding lectin, MBL, belongs to the C-type family of collectins. It functions as an opsonin which activates the alternative pathway of the complement system on binding to microbial polysaccharides.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for MBL Antibody (NB100-1502)(3)

Publications using NB100-1502

• Reese B, Silwal A, Daugherity E et al. Complement as Prognostic Biomarker and Potential Therapeutic Target in Renal Cell Carcinoma J Immunol 2020-12-01 [PMID: 33158953] (ICC/IF, Mouse)
• Ghouse SM, Vadrevu SK, Manne S et al. Therapeutic Targeting of Vasculature in the Premetastatic and Metastatic Niches Reduces Lung Metastasis J. Immunol. 2020-01-03 [PMID: 31900334] (IHC-Fr, Mouse)
• Saevarsdottir S, Oskarsson OO, Aspelund T et al. Mannan binding lectin as an adjunct to risk assessment for myocardial infarction in individuals with enhanced risk. J Exp Med 2005-01-03 [PMID: 15623574]

Bioinformatics

• Gene Symbol: MBL2
• Entrez:
  • 4153(Human)
• Uniprot:
  • NP_000233.(Human)