Matrilin-1 Antibody

Images

 
Western Blot: Matrilin-1 Antibody [NBP1-76325] - Mouse liver tissue lysate with MATN1 antibody at (A) 1 and (B) 2 ug/mL.

Product Details

Summary
Reactivity Hu, Mu, RtSpecies Glossary
Applications WB, ELISA
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
1 mg/ml

Order Details

Matrilin-1 Antibody Summary

Immunogen
Antibody was raised against a 12 amino acid synthetic peptide from near the amino terminus of human MATN1. The immunogen is located within amino acids 120 - 170 of MATN1.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
MATN1
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • Western Blot 1:100-1:2000
  • ELISA 1:100-1:2000
Control Peptide
Matrilin-1 Peptide (NBP1-76325PEP)

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS
Preservative
0.02% Sodium Azide
Concentration
1 mg/ml
Purity
Immunogen affinity purified

Alternate Names for Matrilin-1 Antibody

  • cartilage matrix protein
  • CMP
  • CRTM
  • MATN1
  • matrilin 1, cartilage matrix protein
  • Matrilin1
  • Matrilin-1

Background

Matrilins (MATNs) are a family of non-collagenous extra-cellular matrix (ECM) proteins consisting of four known members that have been proposed to play key roles in modulating cellular phenotypes during chondrogenesis of mesenchymal stem cells (MSCs). MATN1 and MATN3 are expressed specifically in cartilage and are among the most up-regulated ECM proteins during chondrogenesis. MATN1 is composed of two Willebrand Factor A (vWFA) domains separated by one EGF-like domain, whereas MATN3 is composed of a single N-terminal vWFA domain followed by four epidermal growth factor (EGF) repeats and a coiled-coil domain. MATN1 or MATN3 may play a role in modulating chondrogenesis during the chondrocyte differentiation process. Mutations of this gene have been associated with variety of inherited chondrodysplasias. Recent studies show that the MATN1 promoter region was associated with both susceptibility and disease progression in Adolescent idiopathic scoliosis.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics Tool for Matrilin-1 Antibody (NBP1-76325)

Discover related pathways, diseases and genes to Matrilin-1 Antibody (NBP1-76325). Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
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Diseases for Matrilin-1 Antibody (NBP1-76325)

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Bioinformatics

Gene Symbol MATN1
Entrez
Uniprot