Matrilin-1 Antibody - BSA Free

Western Blot: Matrilin-1 Antibody [NBP1-77350] - Rat liver tissue lysate with MATN1 antibody at (A) 1 and (B) 2 ug/mL.

Immunocytochemistry/ Immunofluorescence: Matrilin-1 Antibody - BSA Free [NBP1-77350] - Immunofluorescence of Matrilin-1 in Human Liver cells with Matrilin-1 antibody at 20 u/mL.

Immunohistochemistry: Matrilin-1 Antibody - BSA Free [NBP1-77350] - Immunohistochemistry of Matrilin-1 in human liver tissue with Matrilin-1 antibody at 5 ug/mL.

• Reactivity: Hu, Mu, Rt, Ch
• Applications: WB, ELISA, ICC/IF, IHC
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free
• Concentration: 1 mg/ml

Matrilin-1 Antibody - BSA Free Summary

• Description: Novus Biologicals Rabbit Matrilin-1 Antibody - BSA Free (NBP1-77350) is a polyclonal antibody validated for use in IHC, WB, ELISA and ICC/IF. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: Antibody was raised against a 13 amino acid synthetic peptide from near the carboxy terminus of human MATN1. The immunogen is located within amino acids 370 - 420 of MATN1. Amino Acid Squence: DYINDAAKKAKDL
• Predicted Species: Chicken (92%). Backed by our 100% Guarantee.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: MATN1
• Purity: Peptide affinity purified

Applications/Dilutions

• Dilutions:
  • ELISA 1:100-1:2000
  • Immunocytochemistry/ Immunofluorescence 20 ug/mL
  • Immunohistochemistry 5 ug/ml
  • Immunohistochemistry-Paraffin 5 ug/ml
  • Western Blot 1-2 ug/ml
• Theoretical MW: 54 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
• Control Peptide:

  Matrilin-1 Peptide (NBP1-77350PEP)

Packaging, Storage & Formulations

• Storage: Store at 4C.
• Buffer: PBS
• Preservative: 0.02% Sodium Azide
• Concentration: 1 mg/ml
• Purity: Peptide affinity purified

Alternate Names for Matrilin-1 Antibody - BSA Free

• cartilage matrix protein
• CMP
• CRTM
• MATN1
• matrilin 1, cartilage matrix protein
• Matrilin1
• Matrilin-1

Background

Matrilins (MATNs) are a family of non-collagenous extra-cellular matrix (ECM) proteins consisting of four known members that have been proposed to play key roles in modulating cellular phenotypes during chondrogenesis of mesenchymal stem cells (MSCs). MATN1 and MATN3 are expressed specifically in cartilage and are among the most up-regulated ECM proteins during chondrogenesis. MATN1 is composed of two Willebrand Factor A (vWFA) domains separated by one EGF-like domain, whereas MATN3 is composed of a single N-terminal vWFA domain followed by four epidermal growth factor (EGF) repeats and a coiled-coil domain. MATN1 or MATN3 may play a role in modulating chondrogenesis during the chondrocyte differentiation process. Mutations of this gene have been associated with variety of inherited chondrodysplasias. Recent studies show that the MATN1 promoter region was associated with both susceptibility and disease progression in Adolescent idiopathic scoliosis.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: MATN1
• Entrez:
  • 4146(Human)
  • 17180(Mouse)
  • 297894(Rat)
• Uniprot:
  • P21941(Human)