NIH-3T3 mouse embryonic fibroblast cell line was stained with Goat Anti-Mouse Lymphotoxin beta R/TNFRSF3 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF1008, filled histogram) or isotype control antibody ...read more
Detects mouse Lymphotoxin beta R/TNFRSF3 in direct ELISA and Western blots. In direct ELISAs, approximately 5% cross-reactivity with recombinant human (rh) LT beta R is observed, and less than 1% cross-reactivity with recombinant mouse (rm) 4-1BB, rmCD27, rmOPG, rmRANK, rmCD30, rmCD40, rhDR6, rmTNF RI, rmTNF RII, rmEDAR, rmFas and rmGITR is observed.
Source
N/A
Isotype
IgG
Clonality
Polyclonal
Host
Goat
Gene
LTBR
Purity Statement
Antigen Affinity-purified
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Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20 to -70 °C as supplied.
1 month, 2 to 8 °C under sterile conditions after reconstitution.
6 months, -20 to -70 °C under sterile conditions after reconstitution.
Buffer
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
Preservative
No Preservative
Concentration
LYOPH
Reconstitution Instructions
Reconstitute at 0.2 mg/mL in sterile PBS.
Notes
This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.
Alternate Names for Lymphotoxin beta R/TNFRSF3 Antibody [Unconjugated]
CD18
D12S370
ltbetar
LT-BETA-R
LTBR
lymphotoxin B receptor
Lymphotoxin beta R
lymphotoxin beta receptor (TNFR superfamily, member 3)
Lymphotoxin-beta receptor
LymphotoxinbR
TNF RIII
TNF Rrp
TNFCRTNF-RIII
TNFR superfamily, member 3
TNFR2-RP
TNFR3
TNF-R-III
TNFR-RP
TNFRSF3
TNFRSF3TNFR-III
Tumor necrosis factor C receptor
Tumor necrosis factor receptor 2-related protein
tumor necrosis factor receptor superfamily member 3
tumor necrosis factor receptor superfamily, member 3
Tumor necrosis factor receptor type III
Background
Lymphotoxin beta R is a member of the TNF receptor superfamily and is now designated TNFRSF3. Lymphotoxin beta R transduces signals following binding of LIGHT or the heterotrimeric Lymphotoxins LT alpha 1/ beta 2 or LT alpha 2/ beta 1. It plays a critical role in controlling cellular immune functions and lymphoid organogenesis.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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