LXR alpha/NR1H3 Antibody

Images

 
Western Blot: LXR alpha/NR1H3 Antibody [NBP1-77106] - Rat liver tissue lysate at (A) 1 and (B) 2 ug/mL.
Immunocytochemistry/ Immunofluorescence: LXR alpha/NR1H3 Antibody [NBP1-77106] - Immunofluorescence of LXR-A in rat liver tissue with LXR-A antibody at 20 ug/mL.
Immunohistochemistry-Paraffin: LXR alpha/NR1H3 Antibody [NBP1-77106] - Rat liver tissue with LXR-A antibody at 5 ug/mL.

Product Details

Summary
Reactivity Hu, Mu, RtSpecies Glossary
Applications WB, ELISA, ICC/IF, IHC, IHC-P
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
1 mg/ml

Order Details

LXR alpha/NR1H3 Antibody Summary

Immunogen
Antibody was raised against a 15 amino acid synthetic peptide from near the amino terminus human LXR-A. The immunogen is located within amino acids 50 - 100 of LXR-A.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
NR1H3
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1:100-1:2000
  • ELISA 1:100-1:2000
  • Immunocytochemistry/Immunofluorescence 20 ug/mL
  • Immunohistochemistry 1:10-1:500
  • Immunohistochemistry-Paraffin 1:10-1:500
Theoretical MW
46 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Control Peptide
LXR alpha/NR1H3 Peptide (NBP1-77106PEP)
Publications
Read Publication using NBP1-77106.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS
Preservative
0.02% Sodium Azide
Concentration
1 mg/ml
Purity
Immunogen affinity purified

Alternate Names for LXR alpha/NR1H3 Antibody

  • alpha
  • Liver X receptor alpha
  • liver X receptor-alpha
  • LXR alpha
  • LXRA
  • NR1H3
  • Nuclear receptor subfamily 1 group H member 3
  • nuclear receptor subfamily 1, group H, member 3
  • oxysterols receptor LXR-alpha
  • RLD-1

Background

LXR-A belongs to the Liver X Receptor family that encodes highly homologous transcription factors. Like the highly homologous LXR-B, LXR-A forms heterodimers with the retinoic acid receptor RXRalpha, function as sensors for cellular oxysterols which when activated, increase the expression of genes that control sterol and fatty acid metabolism and homeostasis. Recent experiments have indicated that the LXRs can also modulate both innate and adaptive immune responses. Human and mouse tumors produce LXR ligands that inhibit CCR7 expression on maturing dendritic cells (DCs), thereby allowing tumor immunoescape. In mouse models, it was shown that ablating LXR-A signaling led to an immune-mediated strong inhibition of tumor growth, suggesting that manipulation of this pathway may be a viable anti-cancer approach.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Customers Who Viewed This Item Also Viewed...

NB100-74457
Species: Hu, Mu, Rt
Applications: WB, ICC/IF
NB400-157
Species: Hu, Mu, Po, Pm
Applications: WB, Simple Western
NB400-153
Species: Hu
Applications: WB, ICC/IF
NB400-105
Species: Hu, Mu, Rt, Po, Ca, Ch, Ha, Md
Applications: WB, Simple Western, ChIP, ELISA, Flow, ICC/IF, IHC, IHC-Fr, IHC-P, IP, GS
PP-H4417-00
Species: Hu
Applications: WB, IP, DirELISA
NB300-537
Species: Hu, Mu, Rt, Bv, Rb
Applications: WB, ChIP, Flow, GS, ICC/IF, IHC, IHC-P, IP
NBP2-34260
Species: Hu, Mu, Po, Bv, Rb
Applications: WB, Flow, ICC/IF, IHC-Fr, IHC-P, IP, PAGE
PP-N4111-00
Species: Hu
Applications: WB, IHC, IP
NBP2-22106
Species: Hu, Mu
Applications: WB, IHC, IHC-P
PP-H4537-00
Species: Hu
Applications: WB, IHC, IP, DirELISA
NB100-56603
Species: Hu, Pm
Applications: WB, IHC, IHC-P
NB600-582
Species: Hu, Mu, Rt, Ca, Ch, SyHa, Ha
Applications: WB, Simple Western
NB400-114
Species: Hu, Mu, Rt, Po, Ch, Ha, Pl, Pm
Applications: WB, ICC/IF, IHC, IHC-P, IP
NBP2-29942
Species: Hu
Applications: WB, Flow, IHC-P
NBP2-24493
Species: Hu, Mu, Bv, Ch, Eq, Op, Pm
Applications: WB
NBP2-46522
Species: Hu
Applications: WB, IHC

Publications for LXR alpha/NR1H3 Antibody (NBP1-77106)(1)

Reviews for LXR alpha/NR1H3 Antibody (NBP1-77106) (0)

There are no reviews for LXR alpha/NR1H3 Antibody (NBP1-77106). By submitting a review you will receive an Amazon e-Gift Card or Novus Product Discount.
  • Review with no image -- $10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen
  • Review with an image -- $25/€18/£15/$25 CAD/¥150 Yuan/¥2500 Yen
  • 1st to review with an image -- $50/€35/£30/$50 CAD/¥300 Yuan/¥5000 Yen

Product General Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

Video Protocols

WB Video Protocol
ICC/IF Video Protocol

FAQs for LXR alpha/NR1H3 Antibody (NBP1-77106) (0)

There are no specific FAQs related to this product. Read our general customer & technical service FAQs.

Secondary Antibodies

 

Isotype Controls

Additional LXR alpha/NR1H3 Products

Bioinformatics Tool for LXR alpha/NR1H3 Antibody (NBP1-77106)

Discover related pathways, diseases and genes to LXR alpha/NR1H3 Antibody (NBP1-77106). Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
Visit Tool

Diseases for LXR alpha/NR1H3 Antibody (NBP1-77106)

Discover more about diseases related to LXR alpha/NR1H3 Antibody (NBP1-77106).
 

Pathways for LXR alpha/NR1H3 Antibody (NBP1-77106)

View related products by pathway.

PTMs for LXR alpha/NR1H3 Antibody (NBP1-77106)

Learn more about PTMs related to LXR alpha/NR1H3 Antibody (NBP1-77106).
 

Research Areas for LXR alpha/NR1H3 Antibody (NBP1-77106)

Find related products by research area.

Blogs on LXR alpha/NR1H3

There are no specific blogs for LXR alpha/NR1H3, but you can read our latest blog posts.

Customers Who Bought This Also Bought

Contact Information

Product PDFs

Calculators

Concentration Calculator

The concentration calculator allows you to quickly calculate the volume, mass or concentration of your vial. Simply enter your mass, volume, or concentration values for your reagent and the calculator will determine the rest.

=
÷

Review this Product

Be the first to review our LXR alpha/NR1H3 Antibody and receive a gift card or discount.

Bioinformatics

Gene Symbol NR1H3
Entrez
Uniprot