LXR alpha/NR1H3 Antibody (S07-6A4)

Western Blot: LXR alpha/NR1H3 Antibody (S07-6A4) [NBP3-19682] - Western blot detection of LXR alpha/NR1H3 in Rat Brain lysates using NBP3-19682 (1:1000 diluted). Predicted band size: 50kDa. Observed band size: 50kDa.

Immunohistochemistry-Paraffin: LXR alpha/NR1H3 Antibody (S07-6A4) [NBP3-19682] - Immunohistochemistry of LXR alpha/NR1H3 in paraffin-embedded Human breast cancer tissue using NBP3-19682 at dilution 1/50

• Reactivity: Hu, Mu, Rt
• Applications: WB, IHC
• Clone: S07-6A4
• Clonality: Monoclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Concentration: 0.3 mg/ml

LXR alpha/NR1H3 Antibody (S07-6A4) Summary

• Additional Information: Recombinant Monoclonal Antibody
• Immunogen: A synthetic peptide of human LXR alpha/NR1H3 (Uniprot # Q13133)
• Isotype: IgG
• Clonality: Monoclonal
• Host: Rabbit
• Gene: NR1H3
• Purity: Affinity purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry 1/20
  • Immunohistochemistry-Paraffin
  • Western Blot 1/1000
• Theoretical MW: 50 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.05% BSA
• Preservative: 0.01% Sodium Azide
• Concentration: 0.3 mg/ml
• Purity: Affinity purified

Alternate Names for LXR alpha/NR1H3 Antibody (S07-6A4)

• alpha
• Liver X receptor alpha
• liver X receptor-alpha
• LXR alpha
• LXRA
• NR1H3
• Nuclear receptor subfamily 1 group H member 3
• nuclear receptor subfamily 1, group H, member 3
• oxysterols receptor LXR-alpha
• RLD-1

Background

Liver X Receptors (LXRs) are oxysterol activated nuclear receptors which are involved in the regulation of cholesterol metabolism and bile acids. Two known isoforms, alpha and beta, are differentially expressed. The alpha isoform is predominantly expressed in liver, whereas the beta isoform expression has been shown to be ubiquitous.

LXR antibodies are useful for lipid and cholesterol metabolism studies.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: NR1H3