Lumican Antibody

Western Blot: Lumican Antibody [H00004060-D01P] - Analysis of LUM expression in transfected 293T cell line by LUM polyclonal antibody.Lane 1: LUM transfected lysate(38.40 KDa).Lane 2: Non-transfected lysate.

Product Discontinued

Lumican Antibody Summary

• Description: Quality control test: Antibody reactive against mammalian transfected lysate.
• Immunogen: LUM (NP_002336.1, 1 a.a. - 338 a.a.) full-length human protein. MSLSAFTLFLALIGGTSGQYYDYDFPLSIYGQSSPNCAPECNCPESYPSAMYCDELKLKSVPMVPPGIKYLYLRNNQIDHIDEKAFENVTDLQWLILDHNLLENSKIKGRVFSKLKQLKKLHINHNNLTESVGPLPKSLEDLQLTHNKITKLGSFEGLVNLTFIHLQHNRLKEDAVSAAFKGLKSLEYLDLSFNQIARLPSGLPVSLLTLYLDNNKISNIPDEYFKRFNALQYLRLSHNELADSGIPGNSFNVSSLVELDLSYNKLKNIPTVNENLENYYLEVNQLEKFDIKSFCKILGPLSYSKIKHLRLDGNRISETSLPPDMYECLRVANEVTLN
• Specificity: Reacts with lumican.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: LUM
• Purity: Protein A purified

Applications/Dilutions

• Dilutions:
  • Western Blot
• Application Notes: This antibody is reactive against transfected lysate in WB and as a detection antibody in ELISA.

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.4)
• Preservative: No Preservative
• Purity: Protein A purified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for Lumican Antibody

• KSPG lumican
• LDC
• LUM
• lumican proteoglycan
• Lumican
• SLRR2D
• SLRR2DLDCKeratan sulfate proteoglycan lumican

Background

This gene encodes a member of the small leucine-rich proteoglycan (SLRP) family that includes decorin, biglycan, fibromodulin, keratocan, epiphycan, and osteoglycin. In these bifunctional molecules, the protein moiety binds collagen fibrils and the highly charged hydrophilic glycosaminoglycans regulate interfibrillar spacings. Lumican is the major keratan sulfate proteoglycan of the cornea but is also distributed in interstitial collagenous matrices throughout the body. Lumican may regulate collagen fibril organization and circumferential growth, corneal transparency, and epithelial cell migration and tissue repair. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for Lumican Antibody (H00004060-D01P)(2)

Publications using H00004060-D01P

• Gasimli L, Hickey AM, Yang B et al. Changes in glycosaminoglycan structure on differentiation of human embryonic stem cells towards mesoderm and endoderm lineages. BBA General Subjects. 2014-01-01 [PMID: 24412195]
• Gasimli L, Stansfield HE, Nairn AV et al. Structural remodeling of proteoglycans upon retinoic acid-induced differentiation of NCCIT cells. Glycoconj J. 2013-07-01 [PMID: 23053635] (WB, Human)

Bioinformatics

• Gene Symbol: LUM
• Entrez:
  • 4060(Human)
• Uniprot:
  • NP_002336.1(Human)