LST1 Antibody (LST1/02)

Images

 
Western Blot: LST1 Antibody (LST1/02) [NBP1-45072] - Analysis (non-reducing conditions) of LST1 in whole cell lysate of U937 human Caucasian histiocytic lymphoma cell line. Lane 1: immunostaining with Isotype mouse ...read more

Product Details

Summary
Reactivity Hu, MuSpecies Glossary
Applications WB, ICC/IF, IP
Clone
LST1/02
Clonality
Monoclonal
Host
Mouse
Concentration
1 mg/ml

LST1 Antibody (LST1/02) Summary

Immunogen
KLH-fused peptide corresponding to amino acids SSEGPDLRGRDKRGT of human LST1
Specificity
The antibody LST1/02 reacts with an extracellular epitope of LST1, an approximately 6-11 kDa protein expressed as various transmembrane or soluble forms. LST1 is found predominantly on monocytes and dendritic cells. It migrates on SDS PAGE gels as approximately 25-28 kDa molecule.
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
LST1
Purity
Protein A purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Packaging, Storage & Formulations

Storage
Store at 4C. Do not freeze.
Conjugate
Unconjugated
Buffer
PBS (pH 7.4)
Preservative
15mM Sodium Azide
Concentration
1 mg/ml
Purity
Protein A purified

Applications/Dilutions

Dilutions
  • Western Blot 1:1000
  • Immunocytochemistry/Immunofluorescence 1:10-1:2000
  • Immunoprecipitation 1:50
Application Notes
Western Blotting - It migrates on SDS PAGE gels as approximately 25-28 kDa molecule.

Alternate Names for LST1 Antibody (LST1/02)

  • B144D6S49ELST-1
  • leucocyte specific transcript 1
  • leukocyte specific transcript 1
  • leukocyte-specific transcript 1 protein
  • lymphocyte antigen 117
  • MGC119006
  • MGC119007
  • Protein B144

Background

LST1 (leukocyte-specific transcript, also known as B144) is expressed in cells of myeloid/erythroid lineage (monocytes, granulocytes, dendritic cells, platelets, erythrocytes). At least 14 alternatively spliced variants (LST1/A R11; LST1/N) can be detected; some of them (LST1/A, B, C, G, I, K) are transmembrane cell surface-exposed forms, the other are soluble. LST1 induces production of long, thin filopodia in dendritic cells, has an inhibitory effect on lymphocyte proliferation and may have an immunomodulatory role. LST1/A is an 11 kDa transmembrane adaptor present in membrane rafts and forms spontaneously covalent homodimers. Its intracellular domain contains two tyrosine motifs, one of them being an ITIM very similar to such motifs in Siglec.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

Video Protocols

WB Video Protocol
ICC/IF Video Protocol

FAQs for LST1 Antibody (NBP1-45072) (0)

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Secondary Antibodies

 

Isotype Controls

Other Available Formats

Alexa Fluor 405 Labeled NBP1-45072AF405
Alexa Fluor 488 Labeled NBP1-45072AF488
Alexa Fluor 647 Labeled NBP1-45072AF647
Alexa Fluor 700 Labeled NBP1-45072AF700
Allophycocyanin Labeled NBP1-45072APC
DyLight 350 Labeled NBP1-45072UV
DyLight 405 Labeled NBP1-45072V
DyLight 405LS Labeled NBP1-45072V3
DyLight 488 Labeled NBP1-45072G
DyLight 680 Labeled NBP1-45072FR
DyLight 755 Labeled NBP1-45072IR
PE Labeled NBP1-45072PE
PerCP Labeled NBP1-45072PCP

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Contact Information

Product PDFs

Bioinformatics

Gene Symbol LST1

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