LIN-28B Antibody [Janelia Fluor® 646]

• Reactivity: Hu
• Applications: WB, IHC
• Clonality: Polyclonal
• Host: Sheep
• Conjugate: Janelia Fluor 646

LIN-28B Antibody [Janelia Fluor® 646] Summary

• Immunogen: E. coli-derived recombinant human LIN-28B
  Val83-Thr250
  Accession # Q6ZN17
• Specificity: Detects human LIN-28B in direct ELISAs and Western blots. In direct ELISAs, less than 4% cross-reactivity with recombinant human LIN-28A is observed.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Sheep
• Gene: LIN28B
• Purity: Antigen Affinity-purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Antigen Affinity-purified

Notes

Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

Alternate Names for LIN-28B Antibody [Janelia Fluor® 646]

• CSDD2
• CSDD2protein lin-28 homolog B
• FLJ16517
• lin-28 homolog B (C. elegans)
• Lin-28.2
• LIN28B
• LIN-28B

Background

Lin28B acts as a suppressor of microRNA (miRNA) biogenesis by specifically binding the precursor let-7 (pre-let-7),a miRNA precursor. Acts by binding pre-let-7 and recruiting ZCCHC11/TUT4 uridylyltransferase, leading to the terminaluridylation of pre-let-7. Urid

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: LIN28B