LIGHT/TNFSF14 Antibody (Chris-2)

Product Discontinued

LIGHT/TNFSF14 Antibody (Chris-2) Summary

• Immunogen: Recombinant human LIGHT extracellular domain (aa 89-240).
• Isotype: IgG2b
• Clonality: Monoclonal
• Host: Mouse
• Gene: TNFSF14
• Purity: Protein G purified

Applications/Dilutions

• Dilutions:
  • ELISA 1:100-1:2000
  • Flow Cytometry 1:10-1:1000
  • Western Blot 1:1000
• Application Notes: NBP1-97597 is >95% pure by SDS-PAGE. It is useful in ELISA, Flow Cytometry and Western Blot.

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS
• Preservative: 0.02% Sodium Azide
• Concentration: 1.0 mg/ml
• Purity: Protein G purified

Alternate Names for LIGHT/TNFSF14 Antibody (Chris-2)

• CD258 antigen
• CD258
• delta transmembrane LIGHT
• Herpes virus entry mediator ligand
• Herpesvirus entry mediator ligand
• HVEM-L
• HVEMLherpesvirus entry mediator-ligand
• ligand for herpesvirus entry mediator
• LIGHT
• LIGHTherpesvirus entry mediator A
• LTg
• TNFSF14
• TR2
• tumor necrosis factor (ligand) superfamily, member 14
• tumor necrosis factor ligand superfamily member 14
• tumor necrosis factor receptor-like 2
• tumor necrosis factor superfamily member LIGHT

Background

TNFSF14 is encoded by this gene is a member of the tumor necrosis factor (TNF) ligand family. This protein is a ligand for TNFRSF14, which is a member of the tumor necrosis factor receptor superfamily, and which is also known as a herpesvirus entry mediator (HVEM). This protein may function as a costimulatory factor for the activation of lymphoid cells and as a deterrent to infection by herpesvirus. This protein has been shown to stimulate the proliferation of T cells, and trigger apoptosis of various tumor cells. This protein is also reported to prevent tumor necrosis factor alpha mediated apoptosis in primary hepatocyte. Two alternatively spliced transcript variant encoding distinct isoforms have been reported.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Review for LIGHT/TNFSF14 Antibody (NBP1-97597) (1)

Average Rating: 5

(Based on 1 review)

We have 1 review tested in 1 species: Human.

reviewed by: Verified Customer WB Human 06/01/2018

Summary

• Application: Western Blot
• Sample Tested: Recombinant protein
• Species: Human
• Lot: 06011737

Comments

• Comments: Stained with mouse anti-human LIGHT/TNFSF14 (Chris-2; 1ug/mL) overnight at 4C, followed by IRdye 680 goat anti-mouse (Licor#926-68070; 1:10,000) for 1 hour at room-temperature.

Bioinformatics

• Gene Symbol: TNFSF14