LIF Recombinant Protein


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Product Details

Reactivity HuSpecies Glossary
Applications PAGE
1 mg/ml

Order Details

LIF Recombinant Protein Summary

A recombinant protein with a His-GST tag and corresponding to amino acids 23 - 202 of LIF.

Source: E. coli



Packaging, Storage & Formulations

Store at -80C. Avoid freeze-thaw cycles.
20mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 20% glycerol, 50mM NaCl
1 mg/ml


Application Notes
The purity of this protein is > 90% by SDS-PAGE. Molecular weight is 47.2 kDa (415aa) confirmed by MALDI-TOF

Reactivity Notes


Alternate Names for LIF Recombinant Protein

  • CDF
  • D factor
  • DIA
  • differentiation inhibitory activity
  • differentiation stimulating factor
  • Differentiation-stimulating factor
  • Emfilermin
  • HILDAcholinergic differentiation factor
  • leukemia inhibitory factor (cholinergic differentiation factor)
  • leukemia inhibitory factor
  • Melanoma-derived LPL inhibitor


Leukemia inhibitory factor, also known as LIF, is a pleiotropic cytokine that is expressed by a wide variety of cells including activated T lymphocytes, monocytes, mast cells and neuronal cells. It is involved in the induction of hematopoietic differentiation in normal and myeloid leukemia cells, induction of neuronal cell differentiation, regulator of mesenchymal to epithelial conversion during kidney development, and may also have a role in immune tolerance at the maternal-fetal interface. Recombinant human LIF protein, fused to His GST-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.


This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

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Blogs on LIF.

KLF4 as a transcription factor in stem cell differentiation
Kru¨ppel-like factors (KLFs) are evolutionarily conserved zinc finger transcription factors that play a role in cell differentiation, proliferation, and pluripotency. KLF4 has specifically been tied to many diverse cellular processes, including sel...  Read full blog post.

Contact Information

Product PDFs


Gene Symbol LIF

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