LIF Products

Antibodies
LIF Antibody [Unconjugated]
LIF Antibody [Unconjugated]
AF-250-NA
Species: Hu
Applications: IHC, Neut
Host: Goat Polyclonal
Conjugate Catalog # Availability Size Price
LIF Antibody [Unconjugated]
LIF Antibody [Unconjugated]
AF449
Species: Mu
Applications: WB, Neut
Host: Goat Polyclonal
Conjugate Catalog # Availability Size Price
ELISA Kits
LIF ELISA Kit
LIF ELISA Kit
NBP1-91186
Species: Hu
Applications: ELISA
LIF ELISA Kit [Biotin]
LIF ELISA Kit [Biotin]
KA1740
Species: Hu
Lysates
LIF Overexpression Lysate (De ...
LIF Overexpression Lysate (Denatured)
H00003976-T01
Species: Hu
Applications: WB
LIF Overexpression Lysate (Na ...
LIF Overexpression Lysate (Native)
NBP2-04224
Applications: WB
Proteins
Human LIF Protein
Human LIF Protein
NBP2-34935
Species: Hu
Applications: Func, PAGE
Mouse LIF Protein
Mouse LIF Protein
NBP2-35153
Species: Mu
Applications: Func, PAGE
Rat LIF Protein
Rat LIF Protein
NBP2-35263
Species: Rt
Applications: Func, PAGE

Description

LIF (leukemia inhibitory factor, myeloid leukemia inhibitory factor) a pleiotropic lymphoid factor was initially described as a factor that inhibits the proliferation of myeloid leukemia cells and induces their differentiation into macrophages. Other activities of LIF include inhibition of adipogenesis, cholinergic neuron differentiation and bone metabolism. Human and mouse LIF share 78% homology and activities of LIF are not species-specific. Human LIF is active on mouse cells, but murine LIF is not active on human cells. Benefits of NovActive® Proteins
Fully Active
-Fully folded naturally by eukaryotic source
-Comparable for eukaryotic glycosylation
BioRisk Free
-animal-free
-serum-free
-endotoxin-free
-infection reagent-free
-low in proteolyic activity
-low in pyrogenic and pro-inflammatory activity
Just reconstitute and add to your cell culture.
Have FDA G.R.A.S. (generally recognized as safe) approval.
Advantages of barley endosperm Folding -Proficient protein machinery, with eukaryotic folding, allows for native formation of the protein and long term protection and storage. Environment -A biochemically inert environment, void of endotoxins, low protease activity and secondary metabolite content, and a simple protein profile, aid in downstream processing in barley. FDA G.R.A.S status -Barley is recognized by the FDA as having G.R.A.S (generally recognized as safe) status.

Bioinformatics

Entrez Human
Mouse
Uniprot Human
Human
Human
Product By Gene ID 3976
Alternate Names
  • D factor
  • Emfilermin
  • MLPLI
  • leukemia inhibitory factor
  • Melanoma-derived LPL inhibitor
  • differentiation stimulating factor
  • Differentiation-stimulating factor
  • differentiation inhibitory activity
  • CDF
  • HILDAcholinergic differentiation factor
  • DIA
  • leukemia inhibitory factor (cholinergic differentiation factor)

Research Areas for LIF

Find related products by research area and learn more about each of the different research areas below.

Biologically Active Proteins
Cell Cycle and Replication
Stem Cell Lines

Bioinformatics Tool for LIF

Discover related pathways, diseases and genes to LIF. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
Vizit™, under license from BioVista Inc.

Related LIF Blog Posts

Check out the latest blog posts on LIF.
Using a STAT3 antibody in chromatin immunoprecipitation (ChIP)
Signal transducer and activator of transcription 3 (STAT3) is an important oncogenic transcriptional factor that mediates tumor induced immune suppression.  Specifically, STAT3 transmits signals from cytokines and growth factor receptors in the pla...    Read more.
KLF4 as a transcription factor in stem cell differentiation
Kru¨ppel-like factors (KLFs) are evolutionarily conserved zinc finger transcription factors that play a role in cell differentiation, proliferation, and pluripotency. KLF4 has specifically been tied to many diverse cellular processes, including sel...    Read more.
Read more LIF related blogs.