Laminin gamma 1 Antibody (A5) [Alexa Fluor® 594]

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Product Details

Summary
Reactivity Hu, Mu, BvSpecies Glossary
Applications Flow, IHC, IHC-P, ICC/IF
Clone
A5
Clonality
Monoclonal
Host
Rat
Conjugate
Alexa Fluor 594

Order Details

Laminin gamma 1 Antibody (A5) [Alexa Fluor® 594] Summary

Immunogen
Murine EHS laminin preparation
Localization
Basement membrane
Specificity
Laminins are large hetero-trimeric, non-collagenous glycoproteins composed of alpha, beta, and gamma chains. This MAb reacts with laminin B2/1 chain of ~210kDa and does not cross-react with other basement membrane components or fibronectin. Its specificity was established by immunoprecipitation and immunofluorescence of human skeletal muscle and kidney with laminin chain-specific MAbs. Epithelial sheets in vivo are separated from the mesenchymal elements of the stroma by a thin layer of a specialized type of extracellular matrix termed the basement membrane (BM). This structure consists of individual components, some of which are ubiquitous in BMs and some are not. The ubiquitous ones comprise laminin (LN), entactin/nidogen (EN), collagen type IV (CIV), and large heparan sulfate proteoglycan (HSPG), which interact specifically with each other to form a continuous and regular BM. Alterations of BM integrity, from local discontinuities up to complete loss, are described in many types of human and animal epithelial neoplasms. This MAb stains uniformly all human and murine basement membranes.
Isotype
IgG2a Kappa
Clonality
Monoclonal
Host
Rat
Gene
LAMC1
Purity
Protein A or G purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Flow Cytometry
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
  • Immunofluorescence
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Reactivity Notes

Bovine reported by a verified customer review.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein A or G purified

Notes



Alexa Fluor (R) products are provided under an intellectual property license from Life Technologies Corporation. The purchase of this product conveys to the buyer the non-transferable right to use the purchased product and components of the product only in research conducted by the buyer (whether the buyer is an academic or for-profit entity). The sale of this product is expressly conditioned on the buyer not using the product or its components, or any materials made using the product or its components, in any activity to generate revenue, which may include, but is not limited to use of the product or its components: (i) in manufacturing; (ii) to provide a service, information, or data in return for payment; (iii) for therapeutic, diagnostic or prophylactic purposes; or (iv) for resale, regardless of whether they are resold for use in research. For information on purchasing a license to this product for purposes other than as described above, contact Life Technologies Corporation, 5791 Van Allen Way, Carlsbad, CA 92008 USA or outlicensing@lifetech.com. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for Laminin gamma 1 Antibody (A5) [Alexa Fluor® 594]

  • LAMB2Laminin-7 subunit gamma
  • LAMC1
  • Laminin B2 chain
  • Laminin B2
  • Laminin gamma 1
  • laminin subunit gamma-1
  • laminin, gamma 1 (formerly LAMB2)
  • Laminin-1 subunit gamma
  • Laminin-10 subunit gamma
  • Laminin-11 subunit gamma
  • Laminin-2 subunit gamma
  • Laminin-3 subunit gamma
  • Laminin-4 subunit gamma
  • Laminin-6 subunit gamma
  • Laminin-8 subunit gamma
  • Laminin-9 subunit gamma
  • MGC87297
  • S-LAM gamma
  • S-laminin subunit gamma

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

Isotype Controls

Other Available Formats

Alexa Fluor 350 NBP2-47842AF350
Alexa Fluor 405 NBP2-47842AF405
Alexa Fluor 488 NBP2-47842AF488
Alexa Fluor 532 NBP2-47842AF532
Alexa Fluor 594 NBP2-47842AF594
Alexa Fluor 647 NBP2-47842AF647
Alexa Fluor 700 NBP2-47842AF700
Alexa Fluor 750 NBP2-47842AF750
Allophycocyanin NBP2-47842APC
Biotin NBP2-47842B
DyLight 350 NBP2-47842UV
DyLight 405 NBP2-47842V
DyLight 488 NBP2-47842G
DyLight 550 NBP2-47842R
DyLight 594 NBP2-47842DL594
DyLight 650 NBP2-47842C
DyLight 680 NBP2-47842FR
DyLight 755 NBP2-47842IR
FITC NBP2-47842F
HRP NBP2-47842H
Janelia Fluor 549 NBP2-47842JF549
Janelia Fluor 646 NBP2-47842JF646
PE NBP2-47842PE
PerCP NBP2-47842PCP

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Bioinformatics

Gene Symbol LAMC1