Laminin gamma 1 Products

Description

Laminins are essential and abundant structural non-collagenous glycoproteins localizing to basement membranes. Basement membranes (cell-associated extracellular matrices (ECMs)) are polymers of Laminins with stabilizing Type IV Collagen networks, Nidogen and several proteoglycans. Basement membranes are found under epithelial layers, around the endothelium of blood vessels, and surrounding muscle, peripheral nerve and fat cells. Formation of basement membranes influences cell proliferation, phenotype, migration, gene expression and tissue architecture. Each Laminin is a heterotrimer of alpha, beta and gamma chain subunits that undergoes cell-secretion and incorporation into the ECM. Laminins can self-assemble, bind to other matrix macromolecules and have unique and shared cell interactions mediated by Integrins, dystroglycan and cognate Laminin receptors. The human Laminin gamma-1 gene maps to chromosome 1q31 and is ubiquitously expressed in tissues that produce basement membranes.

Bioinformatics

Entrez	117036 Rat 226519 Mouse 3915 Human
Uniprot	AAH15586 Human NM_002293 Human NP_002284 Human P11047 Human
Product By Gene ID	3915
Alternate Names	LAMB2Laminin-7 subunit gamma Laminin B2 chain laminin subunit gamma-1 laminin, gamma 1 (formerly LAMB2) Laminin-1 subunit gamma Laminin-10 subunit gamma Laminin-11 subunit gamma Laminin-2 subunit gamma Laminin-3 subunit gamma Laminin-4 subunit gamma Laminin-6 subunit gamma Laminin-8 subunit gamma Laminin-9 subunit gamma MGC87297 S-LAM gamma S-laminin subunit gamma

Research Areas for Laminin gamma 1

Find related products by research area and learn more about each of the different research areas below.

Apoptosis
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Extracellular Matrix
Tumor Suppressors