Lambda5/IGLL1 Antibody [Janelia Fluor® 525]

• Reactivity: Mu
• Applications: WB
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Janelia Fluor 525

Lambda5/IGLL1 Antibody [Janelia Fluor® 525] Summary

• Immunogen: Produced in rabbits immunized with a synthetic peptide corresponding to the center region of the Human Lambda5/IGLL1
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: IGLL1
• Purity: Antigen and protein A Affinity-purified

Applications/Dilutions

• Dilutions:
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Antigen and protein A Affinity-purified

Notes

Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

Alternate Names for Lambda5/IGLL1 Antibody [Janelia Fluor® 525]

• 14.1
• AGM2
• CD179 antigen-like family member B
• CD179b antigen
• CD179b
• Ig lambda-5
• IGL1
• IGL5
• IGL5CD179B
• IGLJ14.1
• IGLL
• IGLL1
• IGO
• IGVPB
• immunoglobulin lambda-like polypeptide 1
• immunoglobulin omega polypeptide chain
• Immunoglobulin omega polypeptide
• immunoglobulin-related 14.1 protein
• Immunoglobulin-related protein 14.1
• Lambda5
• Pre-B lymphocyte-specific protein-2
• VPREB2

Background

The preB cell receptor is found on the surface of proB and preB cells, where it is involved in transduction of signals for cellular proliferation, differentiation from the proB cell to the preB cell stage, allelic exclusion at the Ig heavy chain gene locus, and promotion of Ig light chain gene rearrangements. The preB cell receptor is composed of a membrane-bound Ig mu heavy chain in association with a heterodimeric surrogate light chain. This gene encodes one of the surrogate light chain subunits and is a member of the immunoglobulin gene superfamily. This gene does not undergo rearrangement. Mutations in this gene can result in B cell deficiency and agammaglobulinemia, an autosomal recessive disease in which few or no gamma globulins or antibodies are made. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: IGLL1