Aiolos/IKZF3 Antibody - BSA Free


Western Blot: Aiolos/IKZF3 Antibody [NBP2-24495] - Total protein from Jurkat cells and human tonsil was separated on a 12% gel by SDS-PAGE, transferred to PVDF membrane and blocked in 5% non-fat milk in TBST. The more
Immunocytochemistry/ Immunofluorescence: Aiolos/IKZF3 Antibody [NBP2-24495] - IKZF3 antibody was tested in Jurkat cells at a 1:40 dilution against DyLight 488 (Green). Alpha tubulin and nuclei were counterstained more
Western Blot: Aiolos/IKZF3 Antibody [NBP2-24495] - Analysis of IKZF3 in human spleen lysate in the 1) absence and 2) presence of immunizing peptide using this antibody at 0.25 ug/mL.

Product Details

Reactivity Hu, PmSpecies Glossary
Applications WB, ICC/IF, IHC
BSA Free
1.0 mg/ml

Order Details

Aiolos/IKZF3 Antibody - BSA Free Summary

A portion of amino acids 350-400 of human IKZF3 was used as the immunogen.
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.


  • Immunocytochemistry/Immunofluorescence 1:100
  • Immunohistochemistry
  • Western Blot 0.25 - 1.0 ug/mL
Application Notes
Use in IHC reported in scientific literature (PMID:34207079)
Read Publications using
NBP2-24495 in the following applications:

  • 1 publication
  • IHC
    1 publication
  • WB
    7 publications

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: canine (88%), mouse (88%), rat (88%), equine (82%).

Packaging, Storage & Formulations

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
0.02% Sodium Azide
1.0 mg/ml
Immunogen affinity purified

Alternate Names for Aiolos/IKZF3 Antibody - BSA Free

  • AIO
  • Aiolos
  • IKAROS family zinc finger 3 (Aiolos)
  • Ikaros family zinc finger protein 3
  • IKZF3
  • zinc finger protein Aiolos
  • ZNFN1A3
  • ZNFN1A3subfamily 1A, 3 (Aiolos)


IKZF3 encodes a member of the Ikaros family of zinc-finger proteins. Three members of this protein family (Ikaros, Aiolos and Helios) are hematopoietic-specific transcription factors involved in the regulation of lymphocyte development. This gene product is a transcription factor that is important in the regulation of B lymphocyte proliferation and differentiation. Both Ikaros and Aiolos can participate in chromatin remodeling. Regulation of gene expression in B lymphocytes by Aiolos is complex as it appears to require the sequential formation of Ikaros homodimers, Ikaros/Aiolos heterodimers, and Aiolos homodimers. At least six alternative transcripts encoding different isoforms have been described. [provided by RefSeq]


This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for Aiolos/IKZF3 Antibody (NBP2-24495)(13)

We have publications tested in 1 confirmed species: Human.

We have publications tested in 3 applications: ICC/IF, IHC, WB.

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Showing Publications 1 - 10 of 13. Show All 13 Publications.
Publications using NBP2-24495 Applications Species
Zou Y, Liu B, Li L Et al. IKZF3 deficiency potentiates chimeric antigen receptor T cells targeting solid tumors Cancer letters 2021-10-20 [PMID: 34687790] (WB) WB
Chen H, Liu J, Kaniskan HU Et al. Folate-Guided Protein Degradation by Immunomodulatory Imide Drug-Based Molecular Glues and Proteolysis Targeting Chimeras Journal of medicinal chemistry 2021-08-26 [PMID: 34378936]
Barankiewicz J, Szumera-Cieckiewicz A, Salomon-Perzynski A et al. The CRBN, CUL4A and DDB1 Expression Predicts the Response to Immunomodulatory Drugs and Survival of Multiple Myeloma Patients Journal of Clinical Medicine 2021-06-18 [PMID: 34207079] (IHC, Human) IHC Human
Walker, Z J, Idler, B Et al. Exploiting Protein Translation Dependence in Multiple Myeloma with Omacetaxine-Based Therapy. Clin Cancer Res 2021-02-01 [PMID: 33109736] (ICC/IF, Human) ICC/IF Human
Wang Z, Zhou G, Risu N et al. Lenalidomide Enhances CAR-T Cell Activity Against Solid Tumor Cells Cell Transplant 2020-09-24 [PMID: 32967454] (WB, Human) WB Human
Liu J, Chen H, Ma L et al. Light-induced control of protein destruction by opto-PROTAC Sci Adv 2020-02-01 [PMID: 32128407] (WB, Human) WB Human
Kim E, Ten Hacken E, Sivina M, et al. The BET inhibitor GS-5829 targets chronic lymphocytic leukemia cells and their supportive microenvironment Leukemia 2019-12-20 [PMID: 31862959]
Zhu YX, Shi CX, Bruins LA et al. Identification of lenalidomide resistance pathways in myeloma and targeted resensitization using cereblon replacement, inhibition of STAT3 or targeting of IRF4 Blood Cancer J 2019-02-11 [PMID: 30741931] (WB, Human) WB Human
Costa F, Vescovini R, Bolzoni M et al. Lenalidomide increases human dendritic cell maturation in multiple myeloma patients targeting monocyte differentiation and modulating mesenchymal stromal cell inhibitory properties Oncotarget 2017-08-08 [PMID: 28881793] (WB, Human) WB Human
Uehara T, Minoshima Y, Sagane K et al. Selective degradation of splicing factor CAPERalpha by anticancer sulfonamides. Nat. Chem. Biol. 2017-04-24 [PMID: 28437394]
Show All 13 Publications.

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Gene Symbol IKZF3