IRF7 Antibody - BSA Free

Western Blot: IRF7 Antibody [NBP1-77264] - 293 whole cell lysate with IRF7 antibody at (A) 0.5 and (B) 1 ug/ml.

Immunohistochemistry: IRF7 Antibody - BSA Free [NBP1-77264] - Immunohistochemistry of IRF7 in mouse spleen tissue with IRF7 antibody at 5 ug/mL.

• Reactivity: Hu
• Applications: WB, ELISA, IHC
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free
• Concentration: 1 mg/ml

IRF7 Antibody - BSA Free Summary

• Description: Novus Biologicals Rabbit IRF7 Antibody - BSA Free (NBP1-77264) is a polyclonal antibody validated for use in IHC, WB and ELISA. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: Antibody was raised against a peptide corresponding to 14 amino acids near the center of human IRF7. The immunogen is located within amino acids 220 - 270 of IRF7. Amino Acid Squence: AVETTPSPGPQPAA
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: IRF7
• Purity: Peptide affinity purified

Applications/Dilutions

• Dilutions:
  • ELISA 1:100-1:2000
  • Immunohistochemistry 5 ug/ml
  • Immunohistochemistry-Paraffin 5 ug/ml
  • Western Blot 0.5-1 ug/ml
• Control Peptide:

  IRF7 Peptide (NBP1-77264PEP)

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS
• Preservative: 0.02% Sodium Azide
• Concentration: 1 mg/ml
• Purity: Peptide affinity purified

Alternate Names for IRF7 Antibody - BSA Free

• interferon regulatory factor 7
• interferon regulatory factor-7H
• IRF-7
• IRF7A
• IRF-7H

Background

Interferons (IFNs) are involved in a multitude of immune interactions during viral infections and play a major role in both the induction and regulation of innate and adaptive antiviral mechanisms. During infection, host-virus interactions signal downstream molecules such as transcription factors such as IFN regulatory factor-3 (IRF3) which can act to stimulate transcription of IFN-alpha/beta genes. IRF7 has been shown to play a role in the transcriptional activation of virus-inducible cellular genes, including interferon beta chain genes. IRF7 play a major role in the innate immune pathway, interacting with the Toll-like receptor (TLR) adaptor proteins MyD88 and Tirp/TRAM and functioning as an intermediate TLR4 and TLR9 signaling. There are at least four differentially spliced isoforms of IRF7, although their function has not been clearly established.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: IRF7
• Uniprot:
  • Q92985(Human)