Integrin alpha 1/CD49a Antibody (5E8D9) - Azide and BSA Free

• Reactivity: Hu
• Applications: ICC/IF, B/N
• Clone: 5E8D9
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Unconjugated
• Format: Azide and BSA Free

Integrin alpha 1/CD49a Antibody (5E8D9) - Azide and BSA Free Summary

• Description: Relevant Entrez Gene Numbers: NM_181501
• Immunogen: Purified human integrinAlpha 1.
• Isotype: IgG2a
• Clonality: Monoclonal
• Host: Mouse
• Gene: ITGA1
• Purity: Protein A or G purified

Applications/Dilutions

• Dilutions:
  • Block/Neutralize
  • Immunocytochemistry/ Immunofluorescence 1:10-1:2000
• Theoretical MW: 150 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: 0.1M Tris-Glycine (phH 7.4), 0.15M NaCl
• Preservative: No Preservative
• Purity: Protein A or G purified

Notes

Relevant Entrez Gene Numbers: NM_181501

Alternate Names for Integrin alpha 1/CD49a Antibody (5E8D9) - Azide and BSA Free

• CD49 antigen-like family member A
• CD49a antigen
• CD49a
• Integrin alpha 1
• integrin, alpha 1
• ITGA1
• Laminin and collagen receptor
• very late activation protein 1
• VLA-1
• VLA1integrin alpha-1

Background

Integrin alpha 1 encodes the alpha 1 subunit of integrin receptors. This protein heterodimerizes with the beta 1 subunit to form a cell-surface receptor for collagen and laminin. The heterodimeric receptor is involved in cell-cell adhesion and may play a role in inflammation and fibrosis. The alpha 1 subunit contains an inserted (I) von Willebrand factor type I domain which is thought to be involved in collagen binding. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for Integrin alpha 1/CD49a Antibody (NBP2-29757)(5)

Publications using NBP2-29757

• Zook HN, Quijano JC, Ortiz JA, Donohue C et Al. Activation of ductal progenitor-like cells from adult human pancreas requires extracellular matrix protein signaling iScience 2024-03-04 [PMID: 38433896]
• Hamilton NJI, Lee DDH, Gowers KHC et al. Bioengineered airway epithelial grafts with mucociliary function based on collagen IV- and laminin-containing extracellular matrix scaffolds Eur. Respir. J. 2020-06-01 [PMID: 32444408] (B/N, Human)
• Agostini F, Vicinanza C, Di Cintio F et al. Adipose mesenchymal stromal/stem cells expanded by a GMP compatible protocol displayed improved adhesion on cancer cells in flow conditions Ann Transl Med 2020-04-01 [PMID: 32411756] (B/N, Human)
• Wu D, Witt RL, Harrington DA, Farach-Carson MC Dynamic Assembly of Human Salivary Stem/Progenitor Microstructures Requires Coordinated alpha1 beta1 Integrin-Mediated Motility Front Cell Dev Biol 2019-10-16 [PMID: 31750298] (B/N, Human)
• Li H, Hou Y, Zhang S et al. CD49a regulates the function of human decidual natural killer cells Am. J. Reprod. Immunol. 2019-02-13 [PMID: 30756436] (B/N, Human)

Bioinformatics

• Gene Symbol: ITGA1
• Uniprot:
  • P56199()