Inhibin beta A Antibody (SR4080) - BSA Free

Western Blot: Inhibin beta A Antibody (SR4080) [NBP3-27818] - Western blot analysis of Inhibin beta A expression in Human fetal brain lysate.

• Reactivity: Hu, Mu, Rt
• Applications: WB
• Clone: SR4080
• Clonality: Monoclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free

Inhibin beta A Antibody (SR4080) - BSA Free Summary

• Additional Information: Recombinant Monoclonal Antibody
• Immunogen: A synthesized peptide derived from human Inhibin beta A (Uniprot #: P08476)
• Specificity: Detects endogenous levels of total Inhibin beta A
• Isotype: IgG
• Clonality: Monoclonal
• Host: Rabbit
• Gene: INHBA
• Purity: Affinity purified

Applications/Dilutions

• Dilutions:
  • Western Blot 1:500-1:2000
• Theoretical MW: 43 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.4), 150mM NaCl, 50% glycerol
• Preservative: 0.02% Sodium Azide
• Purity: Affinity purified

Alternate Names for Inhibin beta A Antibody (SR4080) - BSA Free

• Activin Beta A
• Activin beta-A chain
• beta A (activin A, activin AB alpha polypeptide)
• EDF
• erythroid differentiation factor
• Erythroid differentiation protein
• follicle-stimulating hormone-releasing protein
• FRP
• FSH-releasing protein
• INHBA
• inhibin beta A chain
• Inhibin Beta A
• Inhibin Subunit Beta A
• inhibin, beta A
• Inhibin, beta-1

Background

The inhibin beta A subunit joins the alpha subunit to form a pituitary FSH secretion inhibitor. Inhibin has been shown to regulate gonadal stromal cell proliferation negatively and to have tumor-suppressor activity. In addition, serum levels of inhibin have been shown to reflect the size of granulosa-cell tumors and can therefore be used as a marker for primary as well as recurrent disease. Because expression in gonadal and various extragonadal tissues may vary severalfold in a tissue-specific fashion, it is proposed that inhibin may be both a growth/differentiation factor and a hormone. Furthermore, the beta A subunit forms a homodimer, activin A, and also joins with a beta B subunit to form a heterodimer, activin AB, both of which stimulate FSH secretion. Finally, it has been shown that the beta A subunit mRNA is identical to the erythroid differentiation factor subunit mRNA and that only one gene for this mRNA exists in the human genome.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: INHBA