IMP5 Antibody - BSA Free

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Staining of human testis shows moderate cytoplasmic positivity in cells in seminiferous ducts.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Format
BSA Free

Order Details

IMP5 Antibody - BSA Free Summary

Description
Novus Biologicals Rabbit IMP5 Antibody - BSA Free (NBP3-24916) is a polyclonal antibody validated for use in IHC. All Novus Biologicals antibodies are covered by our 100% guarantee.
Immunogen
This antibody has been engineered to specifically recognize the recombinant protein IMP5 using the following amino acid sequence: HTKGWLAQGQGAHGLLIVSRVSDQQCSDTTLAPQDPRQPLADLTIPVAMLHYADMLDILSHTRGEAVVRVAMYAPPEPIID
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
SPPL2C
Purity
Affinity purified
Innovator's Reward
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Applications/Dilutions

Dilutions
  • Immunohistochemistry 1:200 - 1:500
  • Immunohistochemistry-Paraffin 1:200 - 1:500
Application Notes
For IHC-Paraffin, we recommend using Heat-Induced Epitope Retrieval (HIER) with a pH level of 6. This optimized retrieval method ensures the best results for your experiments.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS, pH 7.2, 40% glycerol
Preservative
0.02% Sodium Azide
Purity
Affinity purified

Alternate Names for IMP5 Antibody - BSA Free

  • EC 3.4.23
  • EC 3.4.23.-
  • IMP-5
  • intramembrane protease 5
  • signal peptide peptidase-like 2C
  • SPPL2c
  • SPP-like 2C

Background

IMP5 is a protein that functions as an intramembrane-cleaving aspartic protease, and may have the ability to cleave type II membrance signal peptides in the membrane's hydrophobic plane, and is encoded by a gene made up of 684 amino acids and a mass of approximately 74.5 kDa. Current studies are being done on several diseases and disorders relating to this protein, including suprenuclear palsy, Parkinson's disease, and malaria. IMP5 has also been shown to have interactions with BAP1, TAF1D, and DTNBP1.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol SPPL2C