IL-4 Antibody [DyLight 550]

• Reactivity: Bv
• Applications: WB, ICC/IF
• Clonality: Polyclonal
• Host: Goat
• Conjugate: DyLight 550

IL-4 Antibody [DyLight 550] Summary

• Immunogen: E. coli-derived recombinant bovine IL‑4
  His25-Cys135
  Accession # P30367
• Specificity: Detects bovine IL-4 in direct ELISAs and Western blots. In direct ELISAs, approximately 50% cross-reactivity with recombinant porcine IL-4 is observed, less than 5% cross-reactivity with recombinant human IL-4, recombinant feline IL-4, and recombinant canine IL-4 is observed, and less than 1% cross-reactivity with recombinant mouse IL-4, recombinant rat IL-4, and recombinant rhesus macaque IL-4 is observed.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Goat
• Gene: IL4
• Purity: Antigen Affinity-purified

Applications/Dilutions

• Dilutions:
  • Immunocytochemistry
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Antigen Affinity-purified

Notes

DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for IL-4 Antibody [DyLight 550]

• B cell growth factor 1
• BCDF
• B-cell stimulatory factor 1
• BCGF1
• BCGF-1
• binetrakin
• BSF1
• BSF-1
• IL4
• IL-4
• IL-4B_cell stimulatory factor 1
• IL4E12
• interleukin 4
• interleukin-4
• Lymphocyte stimulatory factor 1
• MGC79402
• pitrakinra

Background

IL-4 (Interleukin 4, B cell stimulatory factor) is a pleiotropic cytokine produced by activated T cells, mast cells and basophils. IL-4 has many different functions including promoting proliferation and differentiation of immunologically competent cells. One of its main functions is regulating differentiation of naive CD4+ T cells into helper Th2 cells, the other main function is regulating B cells IgE and IgG1 production. Human IL-4 shows 50% homology with mouse IL-4, but its activities are species-specific and human IL-4 shows no activity on murine and rat cells.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: IL4