IL-37/IL-1F7 Antibody (B-N37) [Alexa Fluor® 488]

• Reactivity: Hu
• Applications: ELISA
• Clone: B-N37
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Alexa Fluor 488

IL-37/IL-1F7 Antibody (B-N37) [Alexa Fluor® 488] Summary

• Immunogen: Recombinant human IL-37/IL-1F7. Hybridoma: Myeloma X63/AG.8653 x Balb/c node cells
• Specificity: Recognizes both natural and recombinant human IL-37/IL-1F7
• Isotype: IgG1 Kappa
• Clonality: Monoclonal
• Host: Mouse
• Gene: IL37
• Purity: Affinity purified

Applications/Dilutions

• Dilutions:
  • ELISA
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Affinity purified

Notes

Alexa Fluor (R) products are provided under an intellectual property license from Life Technologies Corporation. The purchase of this product conveys to the buyer the non-transferable right to use the purchased product and components of the product only in research conducted by the buyer (whether the buyer is an academic or for-profit entity). The sale of this product is expressly conditioned on the buyer not using the product or its components, or any materials made using the product or its components, in any activity to generate revenue, which may include, but is not limited to use of the product or its components: (i) in manufacturing; (ii) to provide a service, information, or data in return for payment; (iii) for therapeutic, diagnostic or prophylactic purposes; or (iv) for resale, regardless of whether they are resold for use in research. For information on purchasing a license to this product for purposes other than as described above, contact Life Technologies Corporation, 5791 Van Allen Way, Carlsbad, CA 92008 USA or outlicensing@lifetech.com. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for IL-37/IL-1F7 Antibody (B-N37) [Alexa Fluor® 488]

• FIL1 zeta
• FIL1
• FIL1(ZETA)
• FIL1ZFIL1 zeta
• IL-1F7
• IL-1F7IL-1 zeta
• IL1H4IL1F7 (canonical product IL-1F7b)
• IL-1H4IL-1F7b (IL-1H4, IL-1H, IL-1RP1)
• IL-1RP1IL-1X protein
• IL1RP1interleukin 1 family member 7
• IL-1X
• IL37
• IL-37
• interleukin 1 family, member 7 (zeta)
• interleukin 1, zeta
• interleukin-1 family member 7
• Interleukin-1 homolog 4
• interleukin-1 superfamily z
• Interleukin-1 zeta
• Interleukin-1-related protein

Background

IL1F7 is encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine can bind to, and may be a ligand for interleukin 18 receptor (IL18R1/IL-1Rrp). This cytokine also binds to interleukin 18 binding protein (IL18BP), an inhibitory binding protein of interleukin 18 (IL18), and subsequently forms a complex with IL18 receptor beta subunit, and through which it inhibits the activity of IL18. This gene along with eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. Five alternatively spliced transcript variants encoding distinct isoforms have been reported.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: IL37