IL-37/IL-1F7 Products

Description

IL1F7 is encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine can bind to, and may be a ligand for interleukin 18 receptor (IL18R1/IL-1Rrp). This cytokine also binds to interleukin 18 binding protein (IL18BP), an inhibitory binding protein of interleukin 18 (IL18), and subsequently forms a complex with IL18 receptor beta subunit, and through which it inhibits the activity of IL18. This gene along with eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. Five alternatively spliced transcript variants encoding distinct isoforms have been reported.

Bioinformatics

Entrez	27178 Human
Uniprot	AAF25212 Human AAH20637 Human NP_055254 Human Q9NZH6 Human
Product By Gene ID	27178
Alternate Names	FIL1 FIL1(ZETA) FIL1ZFIL1 zeta IL-1F7IL-1 zeta IL1H4IL1F7 (canonical product IL-1F7b) IL-1H4IL-1F7b (IL-1H4, IL-1H, IL-1RP1) IL-1RP1IL-1X protein IL1RP1interleukin 1 family member 7 IL-1X interleukin 1 family, member 7 (zeta) interleukin 1, zeta interleukin-1 family member 7 Interleukin-1 homolog 4 interleukin-1 superfamily z Interleukin-1 zeta Interleukin-1-related protein

Research Areas for IL-37/IL-1F7

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Cytokine Research