IL-34 Antibody (578410)

• Reactivity: Hu
• Applications: ELISA(Cap)
• Clone: 578410
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Unconjugated

IL-34 Antibody (578410) Summary

• Immunogen: Mouse myeloma cell line NS0-derived recombinant human IL-34
  Asn21-Pro242
  Accession # Q6ZMJ4
• Specificity: Detects human IL-34 in sandwich immunoassays. In this format, no cross-reactivity with recombinant mouse IL-34 is observed.
• Source: N/A
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Gene: IL34
• Purity Statement: Protein A or G purified from hybridoma culture supernatant

Applications/Dilutions

• Dilutions:
  • ELISA Capture (Matched Antibody Pair) 2-8 ug/mL
  • ELISA Detection (Matched Antibody Pair) 0.5-2.0 ug/mL
  • ELISA Standard (Matched Pair)
• Application Notes: ELISA Detection: Human IL-34 Biotinylated Antibody (Catalog number BAM52652)
  Standard: Recombinant Human IL-34 (Catalog number 5265-IL)

Packaging, Storage & Formulations

• Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.
• Buffer: Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
• Preservative: No Preservative
• Reconstitution Instructions: Reconstitute at 0.5 mg/mL in sterile PBS.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for IL-34 Antibody (578410)

• C16orf77
• IL34
• IL-34
• interleukin 34

Background

Interleukin 34 (IL-34) is secreted as a homodimer consisting of 39 kDa monomers. It belongs to no known cytokine family. The mature chain contains one potential site for N-linked glycosylation. IL-34 is widely expressed, but it is most abundant in the spleen. The receptor for IL-34 is colony-stimulating factor 1 receptor (CSF‑1R). Functionally, IL-34 stimulates monocyte viability.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: IL34
• Uniprot:
  • Q6ZMJ4(Human)