IL-23R Antibody (15N6C6) [DyLight 650]

• Reactivity: Hu, Pm, Pm, Pm-Or
• Applications: WB, IHC
• Clone: 15N6C6
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: DyLight 650

IL-23R Antibody (15N6C6) [DyLight 650] Summary

• Description: This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.
• Immunogen: A synthetic peptide corresponding to amino acids 288-315 of hIL-23 receptor was used as immunogen for this antibody.
• Specificity: There are multiple isoforms of IL-23 receptor. Researchers are encouraged to use a tool like BLAST to determine the suitability of this antibody for their testing.
• Predicted Species: Chimpanzee (100%), Orangutan (94%). Backed by our 100% Guarantee.
• Isotype: IgG1 Kappa
• Clonality: Monoclonal
• Host: Mouse
• Gene: IL23R
• Purity: Protein G purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Reactivity Notes

The amino acid sequence used as immunogen for this antibody is 89% in Mouse, Porcine, Canine and Rhesus Macaque, and 84% homologous in Rat, Equine and Bovine.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Protein G purified

Notes

DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for IL-23R Antibody (15N6C6) [DyLight 650]

• IBD17
• IL-23 R
• IL-23 receptor
• IL23R
• IL-23R
• interleukin 23 receptor
• interleukin-23 receptor

Background

IL23 Receptor is encoded by this gene is a subunit of the receptor for IL23A/IL23. This protein pairs with the receptor molecule IL12RB1/IL12Rbeta1, and both are required for IL23A signaling. This protein associates constitutively with Janus kinase 2 (JAK2), and also binds to transcription activator STAT3 in a ligand-dependent manner.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: IL23R