Mouse IL-12/IL-23 p40 Allele-specific DuoSet ELISA, 15 Plate

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Product Details

Summary
Reactivity MuSpecies Glossary
Applications ELISA
Conjugate
Biotin

Order Details

Mouse IL-12/IL-23 p40 Allele-specific DuoSet ELISA, 15 Plate Summary

Assay Type
Solid Phase Sandwich ELISA
Inter-Assay
See PDF Datasheet for details
Intra-Assay
See PDF Datasheet for details
Spike Recovery
See PDF Datasheet for details
Sample Volume
See PDF Datasheet for details
Gene
Il12b

Applications/Dilutions

Dilutions
  • ELISA
Application Notes
No significant interference observed with available related molecules.
Publications
Read Publications using DY499.

Packaging, Storage & Formulations

Storage
Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Mouse IL-12/IL-23 p40 Allele-specific DuoSet ELISA, 15 Plate

  • CLMF p40
  • CLMF
  • CLMF2
  • Cytotoxic lymphocyte maturation factor 40 kDa subunit
  • IL12 p40
  • IL-12 p40
  • IL-12 subunit p40
  • IL12B
  • IL-12B
  • IL-12BNK cell stimulatory factor chain 2
  • interleukin 12, p40
  • interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocytematuration factor 2, p40)
  • interleukin-12 beta chain
  • interleukin-12 subunit beta
  • natural killer cell stimulatory factor, 40 kD subunit
  • NKSF
  • NKSF2
  • NKSF2IL12, subunit p40

Background

Interleukin 12 (IL-12), also known as natural killer cell stimulatory factor (NKSF) or cytotoxic lymphocyte maturation factor (CLMF), is a heterodimeric pleiotropic cytokine made up of a 40 kDa (p40) subunit and a 35 kDa (p35) subunit. The IL-12 p40 subunit is shared by IL-23, another heterodimeric cytokine that has biological activities similar to, as well as distinct from, IL-12. IL-12 is produced by macrophages and B cells and has been shown to have multiple effects on T cells and natural killer (NK) cells. While mouse IL-12 is active on both human and mouse cells, human IL-12 is not active on mouse cells.

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Publications for IL-12/IL-23 p40 (DY499)(45)

We have publications tested in 1 confirmed species: Mouse.


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Mouse
(43)
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Showing Publications 1 - 10 of 45. Show All 45 Publications.
Publications using DY499 Applications Species
SY Ahn, CTT Le, EJ Ko Monophosphoryl Lipid A and Poly I:C Combination Adjuvant Promoted Ovalbumin-Specific Cell Mediated Immunity in Mice Model Biology, 2021;10(9):. 2021 [PMID: 34571785] (Mouse) Mouse
CC Lin, YR Shen, CC Chang, XY Guo, YY Young, TY Lai, IS Yu, CY Lee, TH Chuang, HY Tsai, LC Hsu Terminal uridyltransferase 7 regulates TLR4-triggered inflammation by controlling Regnase-1 mRNA uridylation and degradation Nature Communications, 2021;12(1):3878. 2021 [PMID: 34188032] (Mouse) Mouse
DC Montrose, R Nishiguchi, S Basu, HA Staab, XK Zhou, H Wang, L Meng, M Johncilla, JR Cubillos-R, DK Morales, MT Wells, KW Simpson, S Zhang, B Dogan, C Jiao, Z Fei, A Oka, JW Herzog, RB Sartor, AJ Dannenberg Dietary Fructose Alters the Composition, Localization and Metabolism of Gut Microbiota in Association with Worsening Colitis Cell Mol Gastroenterol Hepatol, 2020;0(0):. 2020 [PMID: 32961355] (Mouse) Mouse
KD Curtis, PR Smith, HW Despres, JP Snyder, TC Hogan, PD Rodriguez, E Amiel Glycogen Metabolism Supports Early Glycolytic Reprogramming and Activation in Dendritic Cells in Response to Both TLR and Syk-Dependent CLR Agonists Cells, 2020;9(3):. 2020 [PMID: 32183271] (Mouse) Mouse
S Benmerzoug, B Bounab, S Rose, D Gosset, F Biet, T Cochard, A Xavier, N Rouxel, L Fauconnier, WGC Horsnell, B Ryffel, D Togbe, VFJ Quesniaux Sterile Lung Inflammation Induced by Silica Exacerbates Mycobacterium tuberculosis Infection via STING-Dependent Type 2 Immunity Cell Rep, 2019;27(9):2649-2664.e5. 2019 [PMID: 31141689] (Mouse) Mouse
S Vander Bek, JC de Vries, B Meier-Schi, P Meyer, D Jiang, A Sindrilaru, FF Ferreira, A Hainzl, S Schatz, J Muschhamme, NJ Scheurmann, P Kampilafko, AM Seitz, L Dürselen, A Ignatius, MA Kluth, C Ganss, M Wlaschek, K Singh, P Maity, NY Frank, MH Frank, K Scharffett Newly defined ABCB5+ dermal mesenchymal stem cells promote healing of chronic iron overload wounds via secretion of interleukin-1 receptor antagonist Stem Cells, 2019;0(0):. 2019 [PMID: 31002437] (Mouse) Mouse
E Engelowski, NF Modares, S Gorressen, P Bouvain, D Semmler, C Alter, Z Ding, U Flögel, J Schrader, H Xu, PA Lang, J Fischer, DM Floss, J Scheller IL-23R Signaling Plays No Role in Myocardial Infarction Sci Rep, 2018;8(1):17078. 2018 [PMID: 30459442] (Mouse) Mouse
AP Gounder, CC Yokoyama, NN Jarjour, TL Bricker, BT Edelson, ACM Boon Interferon induced protein 35 exacerbates H5N1 influenza disease through the expression of IL-12p40 homodimer PLoS Pathog., 2018;14(4):e1007001. 2018 [PMID: 29698474] (Mouse) Mouse
M Murase, T Kawasaki, R Hakozaki, T Sueyoshi, DDP Putri, Y Kitai, S Sato, M Ikawa, T Kawai Intravesicular Acidification Regulates Lipopolysaccharide Inflammation and Tolerance through TLR4 Trafficking J. Immunol., 2018;0(0):. 2018 [PMID: 29540576] (Mouse) Mouse
SY Lin, SY Hsieh, YT Fan, WC Wei, PW Hsiao, DH Tsai, TS Wu, NS Yang Necroptosis promotes autophagy-dependent upregulation of DAMP and results in immunosurveillance Autophagy, 2017;0(0):0. 2017 [PMID: 29171784] (Mouse) Mouse
Show All 45 Publications.

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Bioinformatics

Gene Symbol Il12b