IL-22 Antibody

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Immunohistochemistry-Paraffin: IL-22 Antibody [NB100-738] - Goat anti-IL-22 antibody on paraffin section of human tonsil.

Product Details

Summary
Reactivity Hu, MuSpecies Glossary
Applications ELISA, IHC, IHC-P
Clonality
Polyclonal
Host
Goat
Conjugate
Unconjugated
Concentration
1.0 mg/ml

Order Details

IL-22 Antibody Summary

Immunogen
Synthetic peptide: LKDTVKKLGESGEIKAIGELDLLFMSLRNA, corresponding to C terminal amino acids 148-177 of Human IL22.
Localization
Secreted
Specificity
IL22
Isotype
IgG
Clonality
Polyclonal
Host
Goat
Gene
IL22
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • ELISA 1:50000
  • Immunohistochemistry 1:150
  • Immunohistochemistry-Paraffin 1:150

Packaging, Storage & Formulations

Storage
Store at -20C. Avoid freeze-thaw cycles.
Buffer
10mM KHPO4 and 0.14M NaCl, pH 7.2
Preservative
0.1% Sodium Azide
Concentration
1.0 mg/ml
Purity
Immunogen affinity purified

Alternate Names for IL-22 Antibody

  • Cytokine Zcyto18
  • IL-10-related T-cell-derived inducible factor
  • IL22
  • IL-22
  • IL-D110
  • IL-TIF
  • ILTIFIL-10-related T-cell-derived-inducible factor
  • IL-TIFMGC79382
  • interleukin 22
  • interleukin-22
  • MGC79384
  • TIFa
  • TIFIL-23
  • zcyto18

Background

IL22 is a cytokine structurally related to IL10 and is upregulated in activated T cells. IL22 signals through a receptor complex that includes CRF2-4 and a new member of the class II cytokine receptor family (also known as the interferon receptor family), IL22R. CRF2-4 has previously been demonstrated to be a functional component of the IL-10 signaling complex. IL22 is able to suppress IL4 production; this may have therapeutic potential, particularly in the treatment of asthma.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics Tool for IL-22 Antibody (NB100-738)

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Research Areas for IL-22 Antibody (NB100-738)

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Blogs on IL-22.

Toll-like receptors in the intestinal epithelial cells
By Jamshed Arslan, Pharm. D., PhD. Toll-like receptors (TLRs) are microbe-sensing proteins that act as first responders to danger signals. TLRs help the intestinal epithelial cells (IECs) recognize commensal bacteria...  Read full blog post.

PPAR gamma - An important target in human metabolism
Peroxisome proliferators are non-genotoxic carcinogens which are purported to exert their effect on cells by interacting with members of the nuclear hormone receptor superfamily known as peroxisome proliferator activated receptors (PPARs). There are f...  Read full blog post.

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Bioinformatics

Gene Symbol IL22
Entrez