IL-22 Antibody - BSA Free

Immunohistochemistry-Paraffin: IL-22 Antibody [NB100-738] - Goat anti-IL-22 antibody on paraffin section of human tonsil.

• Reactivity: Hu, Mu
• Applications: ELISA, IHC
• Clonality: Polyclonal
• Host: Goat
• Conjugate: Unconjugated
• Format: BSA Free
• Concentration: 1.0 mg/ml

IL-22 Antibody - BSA Free Summary

• Immunogen: Synthetic peptide: LKDTVKKLGESGEIKAIGELDLLFMSLRNA, corresponding to C terminal amino acids 148-177 of Human IL22.
• Localization: Secreted
• Specificity: IL22
• Isotype: IgG
• Clonality: Polyclonal
• Host: Goat
• Gene: IL22
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • ELISA 1:50000
  • Immunohistochemistry 1:150
  • Immunohistochemistry-Paraffin 1:150

Packaging, Storage & Formulations

• Storage: Store at -20C. Avoid freeze-thaw cycles.
• Buffer: 10mM KHPO4 and 0.14M NaCl, pH 7.2
• Preservative: 0.1% Sodium Azide
• Concentration: 1.0 mg/ml
• Purity: Immunogen affinity purified

Alternate Names for IL-22 Antibody - BSA Free

• Cytokine Zcyto18
• IL-10-related T-cell-derived inducible factor
• IL22
• IL-22
• IL-D110
• IL-TIF
• ILTIFIL-10-related T-cell-derived-inducible factor
• IL-TIFMGC79382
• interleukin 22
• interleukin-22
• MGC79384
• TIFa
• TIFIL-23
• zcyto18

Background

IL22 is a cytokine structurally related to IL10 and is upregulated in activated T cells. IL22 signals through a receptor complex that includes CRF2-4 and a new member of the class II cytokine receptor family (also known as the interferon receptor family), IL22R. CRF2-4 has previously been demonstrated to be a functional component of the IL-10 signaling complex. IL22 is able to suppress IL4 production; this may have therapeutic potential, particularly in the treatment of asthma.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: IL22
• Entrez:
  • 50616(Human)
  • 50929(Mouse)