WB, ELISA(Cap), NeutHost:
ELISA, IHC, IHC-PHost:
Applications: WB, IHC-P
Host: Mouse Monoclonal
Applications: Func, PAGE
Applications: RNAi, RNAi SP
Interleukin-22 (IL-22 or IL-TIF (IL-10-related T-cell derived inducible factor)) belongs to the IL-10 family of regulatory cytokines which also includes IL-10, IL-19, IL-20, IL-24 and IL-26. IL-22 is produced by T lymphocytes following anti-CD3 stimulation. It inhibits IL-4 production of Th2 cells, activates STAT-1 and STAT-3 in several hepatoma cell lines and upregulates the production of acute phase proteins. It may also be involved in inflammatory responses. Human and mouse IL-22 share 79% amino acid identity. Recombinant human IL-22 is a non-disulfide linked homodimer, signaling through a receptor complex of two subunits, IL-22R and IL-10R-beta, belonging to the class II cytokine receptor family.
|Product By Gene ID
- interleukin 21
- IL-10-related T-cell-derived inducible factor
- ILTIFIL-10-related T-cell-derived-inducible factor
- Cytokine Zcyto18
- interleukin 22
Bioinformatics Tool for IL-22
Discover related pathways, diseases and genes to IL-22. Need help? Read the Bioinformatics Tool Guide
for instructions on using this tool.
Related IL-22 Blog Posts
Check out the latest blog posts on IL-22.
Read more IL-22 related blogs.
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Peroxisome proliferators are non-genotoxic carcinogens which are purported to exert their effect on cells by interacting with members of the nuclear hormone receptor superfamily known as peroxisome proliferator activated receptors (PPARs). There are f... Read more.