IL-21 Recombinant Protein


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IL-21 Recombinant Protein Summary

A recombinant protein corresponding to 130 amino acids of Mouse IL-21

Source: E. coli

Amino Acid Sequence: The amino acid sequence of this product is not available.
E. coli
Details of Functionality
The bioactivity is determined by a dose-dependent proliferation of lymphocytes co-stimulated with anti-CD3E and is typically 2-50
Endotoxin Note
<0.01 ng/ug

Packaging, Storage & Formulations

Store at -20C. Avoid freeze-thaw cycles.
Reconstitution Instructions
Reconstitute with sterilized water to a final concentration of 0.1 mg/ml.


The purity of this protein is >95% pure by SDS-PAGE

Alternate Names for IL-21 Recombinant Protein

  • IL21
  • IL-21Za11interleukin-21
  • interleukin 21
  • interleukin-21 isoform


Mouse Interleukin-21 (m-IL-21), expressed by activated CD4(+) T cells, is the newest member of the common gamma-chain family of cytokines, which also includes IL-2, IL-4, IL-7, IL-9, and IL-13. Its private receptor, IL-21R, is expressed on T, B, and NK cells. Within the B cell lineage, IL-21 regulates IgG1 production and cooperates with IL-4 for the production of multiple Ab classes in vivo. IL-21R has been shown to activate the Janus kinase/signal transducers and activators of transcription signaling pathways upon ligand binding. Initial studies have demonstrated that IL-21 has pleiotropic effects on the proliferation, the differentiation, and the effector functions of B, T, natural killer, and dendritic cells. Recombinant mouse IL-21, produced in E.coli, is a single, non-glycosylated polypeptide chain containing 130 amino acids and having a total molecular mass of 15,095 Daltons.


This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

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Perforin, also known as the pore-forming protein, pfp, is a 70 kD cytolytic protein expressed in the cytoplasmic granules of cytotoxic T lymphocytes (CTLs) and natural killer (NK) cells. It is one of the major effector molecules used by CTL and NK cel...  Read full blog post.

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Gene Symbol IL21

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