IL-21 Antibody (2B2-G20) [Biotin]

Product Discontinued

IL-21 Antibody (2B2-G20) [Biotin] Summary

• Immunogen: The immunogen for this antibody is IL-21 Interleukin-21 (eBio2B2-G20 (2B2-G20)).
• Isotype: IgG1 Kappa
• Clonality: Monoclonal
• Host: Mouse
• Gene: IL21
• Purity: Protein A or G purified

Applications/Dilutions

• Dilutions:
  • ELISA 1:100-1:2000
• Application Notes: The 2B2-G20 antibody has been tested as the detection antibody in a sandwich ELISA for analysis of human Interleukin-21 (IL-21) in combination with the purified 3A3-N2 antibody for capture and recombinant human IL-21 as the standard. A suitable range of concentrations of this antibody for ELISA capture is 0.5-2 ug/ml. A standard curve consisting of doubling dilutions of the recombinant standard over the range of 4000 pg/ml - 60 pg/ml should be included in each ELISA plate.
• Readout System:
  • Streptavidin Native Protein NBP2-29367
  • Streptavidin Native Protein NBP2-29370
  • Streptavidin Native Protein NBP2-29371

Reactivity Notes

Human

Packaging, Storage & Formulations

• Storage: Store at 4C. Do not freeze.
• Buffer: Aqueous buffer, may contain carrier protein/stabilizer (proprietary)
• Preservative: 0.09% Sodium Azide
• Concentration: 0.5 mg/ml
• Purity: Protein A or G purified

Alternate Names for IL-21 Antibody (2B2-G20) [Biotin]

• CVID11
• IL21
• IL-21
• IL-21Za11interleukin-21
• interleukin 21
• interleukin-21 isoform
• Za11

Background

The monoclonal antibody 2B2-G20 reacts with human IL-21, a potent stimulator of NK and cytolytic T cells. IL-21 is a 131 amino acid protein most closely related to IL-2 and IL-15. Expression is found in CD4+ cells upon activation. In addition to its effect on NK cells, IL-21 stimulates proliferation of B-cell stimulated by crosslinking of the CD40 antigen and stimulates the proliferation of bone marrow progenitor cells and the expression of the NK-cell marker CD56 in the presence of IL-15.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: IL21