IL-2 Antibody (B-G5) - Azide and BSA Free

Flow Cytometry: IL-2 Antibody (B-G5) [NBP3-14593] - The graph on the left represents activated lymphocytes marked with IL-2 antibody. The graph on the right shows IL-2 antibody with non-activated lymphocytes. In the two cases, the dotted line represents the IgG1 isotype control.

• Reactivity: Hu
• Applications: WB, ELISA, Flow, Func, ELISA
• Clone: B-G5
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Unconjugated
• Format: Azide and BSA Free
• Concentration: 1 mg/ml

IL-2 Antibody (B-G5) - Azide and BSA Free Summary

• Description: Hybridoma: Myeloma X63/AG.8653 x Balb/c spleen cells
• Immunogen: Natural human IL-2
• Specificity: recognizes both natural and recombinant human IL-2
• Isotype: IgG1 Kappa
• Clonality: Monoclonal
• Host: Mouse
• Gene: IL2
• Purity: Affinity purified

Applications/Dilutions

• Dilutions:
  • ELISA
  • Enzyme-linked Immunosorbent Spot
  • Flow Cytometry
  • Functional
  • Western Blot
• Application Notes: Biological Activity: Inhibits IL-2 induced proliferation on Kit 225 cell line

Packaging, Storage & Formulations

• Storage: Store at 4C. Do not freeze.
• Buffer: PBS. Sterile-filtered through 0.22 um.
• Preservative: No Preservative
• Concentration: 1 mg/ml
• Purity: Affinity purified

Alternate Names for IL-2 Antibody (B-G5) - Azide and BSA Free

• Aldesleukin
• IL2
• IL-2
• IL-2lymphokine
• interleukin 2
• interleukin-2
• involved in regulation of T-cell clonal expansion
• Proleukin
• T cell growth factor
• T-cell growth factor
• TCGF

Background

Interleukin 2 (IL-2) is a potent immunoregulatory growth factor produced by T-cells following stimulation by mitogens or allogens. IL-2 promotes growth and differentiation of various cells of the immune system, such as activated T-cells and B-cells, NK cells, lymphokine activated killer cells, monocytes and macrophages. It is essential for proper immune response, it may also be an important factor in the natural suppression of autoimmunity. IL2 may be of use as an anti-tumor agent in cancer therapy. Recombinant human IL2 is a 15.5 kDa protein, consisting of 134 amino acid residues. Human and mouse IL-2 share 56% aa sequence identity and exhibit cross-species activity.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: IL2