IGFBP-3 Antibody - Azide and BSA Free

Western Blot: IGFBP-3 Antibody [H00003486-D01P] - Analysis of IGFBP-3 expression in transfected 293T cell line by IGFBP-3 polyclonal antibody. Lane 1: IGFBP3 transfected lysate(31.70 KDa). Lane 2: Non-transfected lysate.

Immunocytochemistry/Immunofluorescence: IGFBP-3 Antibody [H00003486-D01P] - Analysis of antibody to IGFBP3 on HeLa cell. Antibody concentration 20 ug/ml.

• Reactivity: Hu
• Applications: WB, ICC/IF
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: Azide and BSA Free

IGFBP-3 Antibody - Azide and BSA Free Summary

• Description: Quality control test: Antibody reactive against mammalian transfected lysate.
• Immunogen: IGFBP3 (AAH64987.1, 1 a.a. - 291 a.a.) full-length human protein. MQRARPTLWAAALTLLVLLRGPPVARAGASSAGLGPVVRCEPCDARALAQCAPPPAVCAELVREPGCGCCLTCALSEGQPCGIYTERCGSGLRCQPSPDEARPLQALLDGRGLCVNASAVSRLRAYLLPAPPAPGNASESEEDRSAGSVESPSVSSTHRVSDPKFHPLHSKIIIIKKGHAKDSQRYKVDYESQSTDTQNFSSESKRETEYGPCRREMEDTLNHLKFLNVLSPRGVHIPNCDKKGFYKKKQCRPSKGRKRGFCWCVDKYGQPLPGYTTKGKEDVHCYSMQSK
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: IGFBP3
• Purity: Protein G purified

Applications/Dilutions

• Dilutions:
  • Immunocytochemistry/ Immunofluorescence 1:10-1:500
  • Western Blot 1:100-1:2000
• Application Notes: It has been used for WB.

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.4)
• Preservative: No Preservative
• Purity: Protein G purified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for IGFBP-3 Antibody - Azide and BSA Free

• acid stable subunit of the 140 K IGF complex
• binding protein 29
• binding protein 53
• growth hormone-dependent binding protein
• IBP-3
• IBP3BP-53
• IGF-binding protein 3
• IGFBP3
• IGFBP-3
• insulin-like growth factor binding protein 3
• insulin-like growth factor-binding protein 3

Background

This gene is a member of the insulin-like growth factor binding protein (IGFBP) family and encodes a protein with an IGFBP domain and a thyroglobulin type-I domain. The protein forms a ternary complex with insulin-like growth factor acid-labile subunit (IGFALS) and either insulin-like growth factor (IGF) I or II. In this form, it circulates in the plasma, prolonging the half-life of IGFs and altering their interaction with cell surface receptors. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for IGFBP-3 Antibody (H00003486-D01P)(1)

Publication using H00003486-D01P

• Hyeon H, Yong L, Hee L et al. G721-0282 exerts anxiolytic-like effects on chronic unpredictable mild stress in mice through inhibition of CHI3L1-mediated neuroinflammation. Br J Pharmacol. 2020-11-03 [PMID: 33140845]

Bioinformatics

• Gene Symbol: IGFBP3
• Uniprot:
  • AAH64987.1(Human)