Rat ICAM-1/CD54 ELISA Kit (Colorimetric)

Product Discontinued

Rat ICAM-1/CD54 ELISA Kit (Colorimetric) Summary

• Description: Icam1 (Rat) ELISA Kit is a sandwich enzyme immunoassay for the quantitative measurement of rat Icam1.
• Standard Curve Range: 31.2 to 2000 pg/mL
• Sensitivity: 2 pg/mL
• Assay Type: Sandwich ELISA
• Sample Volume: 100 uL
• Kit Type: ELISA Kit (Colorimetric)
• Gene: ICAM1

Applications/Dilutions

• Dilutions:
  • ELISA
• Application Notes: Useful for quantification.

Packaging, Storage & Formulations

• Storage: Store at -20 °C.

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for Rat ICAM-1/CD54 ELISA Kit (Colorimetric)

• BB2
• CD54 antigen
• CD54
• cell surface glycoprotein P3.58
• human rhinovirus receptor
• ICAM1
• ICAM-1
• intercellular adhesion molecule 1 (CD54), human rhinovirus receptor
• intercellular adhesion molecule 1
• Major group rhinovirus receptor
• P3.58

Background

ICAM1 is a 85-110 kDa single chain type 1 integral membrane glycoprotein with an extracellular domain of five immunoglobulin superfamily repeats, a transmembrane region and a cytoplasmic domain. It shares considerable amino acid sequence homology with ICAM3 and with ICAM2. ICAM1 is expressed by activated endothelial cells. It is detected on cells of many other lineages (e.g. epithelial cells, fibroblasts, chondrocytes, B lymphocytes, T lymphocytes (low), monocytes, macrophages, dendritic cells and neutrophils), with lower levels that increase in inflammation. ICAM1 is also detected in some carcinoma and melanoma cells. Soluble ICAM1 is detectable in the plasma and is elevated in patients with various inflammatory syndromes. It is the receptor for rhinoviruses and malaria.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. ELISA Kits are guaranteed for 6 months from date of receipt.

Publications for ICAM-1/CD54 ELISA Kit (KA0346)(5)

Publications using KA0346

• Hamsi MA, Othman F, Das S et al. Effect of consumption of fresh and heated virgin coconut oil on the blood pressure and inflammatory biomarkers: An experimental study in Sprague Dawley rats. Alexandria Journal of Medicine 2014-02-11 (ELISA, Rat)
• Demirta? ?ahin T, Yazir Y, Utkan T et al. Depression induced by chronic stress leads to penile cavernosal dysfunction: protective effect of anti-TNF-? treatment. Can J Physiol Pharmacol 2018-07-27 [PMID: 30052465]
• Demirta? ?ahin T, Yazir Y, Utkan T et al. TNF-? antagonism with etanercept enhances penile NOS expression, cavernosal reactivity, and testosterone levels in aged rats. Can J Physiol Pharmacol 2017-12-20 [PMID: 29260891]
• Aboul-Fotouh S, Elgayar N., et al. Atypical antipsychotics such as risperidone, but not, Paliperidone, Worsens Vascular Endothelial Function via Upregulation of Adhesion Molecules ICAM-1, ICAM-1 and E-selectin in Diabetic Rats. Canadian Journal of Physiology and Pharmacolog 2013-09-03 [PMID: 24289084]
• Ballantyne CM, Kozak CA, O'Brien WE, Beaudet AL. Assignment of the gene for intercellular adhesion molecule-1 (Icam-1) to proximal mouse chromosome 9. Genomics 1991-03-01 [PMID: 1674500]

FAQs for ICAM-1/CD54 ELISA Kit (KA0346). (Showing 1 - 1 of 1 FAQs).

1. What is the difference between the Quantikine and Duoset ELISA kits?
   • Our Quantikine kits are fully optimized and validated for the sample types listed on the product specific webpage and datasheet, as this can vary between kits. Each kit is supplied ready to use with one pre-coated 96-well plate, a detection antibody directly conjugated to HRP, and all other necessary reagents. These kits are ideal for researchers who want the convenience of a ready to use and optimized ELISA product. Some of these kits are also available prepackaged in larger 6 and 50 plate sizes.Our DuoSet Kits, in contrast, are ELISA development kits containing the capture and detection antibody, the mass-value calibrated standard, and streptavidin-HRP to prepare approximately 5 or 15 plates. Ancillary reagents will need to be used/purchased, and for most kits, we will recommend one of our Ancillary Reagent Kits, which contain the reagents we use ourselves in-house. DuoSet kits are validated only for cell culture supernatant samples and therefore require further development and validation for accurate measurement in more complex samples such as serum and plasma. Our DuoSet Kits offer an economical, flexible alternative for the experienced ELISA user.

Bioinformatics

• Gene Symbol: ICAM1