ICAM-1/CD54 Antibody (1H4) [FITC] Summary
Raji cells and spleen cells fused with NS1 cells.
This antibody (clone 1H4) reacts with CD54 (ICAM-1), a 85-110 kDa type I transmembrane glycoprotein (receptor for rhinovirus) expressed on activated endothelial cells, T lymphocytes, B lymphocytes, monocytes, macrophages, granulocytes and dendritic cells; the expression of CD54 is upregulated by activation.
Protein A purified
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Packaging, Storage & Formulations
Store at 4C in the dark.
FITC (A=495, E=519)
PBS and 0.2% (w/v) high grade BSA (protease free)
0.09% Sodium Azide
Protein A purified
The reagent is designed for Flow Cytometry analysis of human blood cells using 20 ul reagent / 100 ul of whole blood or 10^6 cells in a suspension.
Alternate Names for ICAM-1/CD54 Antibody (1H4) [FITC]
- CD54 antigen
- cell surface glycoprotein P3.58
- human rhinovirus receptor
- intercellular adhesion molecule 1 (CD54), human rhinovirus receptor
- intercellular adhesion molecule 1
- Major group rhinovirus receptor
CD54 (ICAM-1) is a 90 kD member of the C2 subset of immunoglobulin superfamily. It is a transmembrane molecule with 7 potential N-glycosylated sites, expressed on resting monocytes and endothelial cells and can be upregulated on many other cells, e.g. with lymphokines, on B- and T-lymphocytes, thymocytes, dendritic cells and also on keratinocytes, chondrocytes, as well as epithelial cells. CD54 mediates cell adhesion by binding to integrins CD11a/CD18 (LFA-1) and to CD11b/CD18 (Mac-1). The interaction of CD54 with LFA-1 enhances antigen-specific T-cell activation.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed
for 1 year from date of receipt.
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