HUS1 Antibody (2B12)

Images

 
Sandwich ELISA: HUS1 Antibody (2B12) [H00003364-M01] - Detection limit for recombinant GST tagged HUS1 is 0.1 ng/ml as a capture antibody.
Immunoprecipitation: HUS1 Antibody (2B12) [H00003364-M01] - Analysis of HUS1 transfected lysate using anti-HUS1 monoclonal antibody and Protein A Magnetic Bead, and immunoblotted with HUS1 MaxPab rabbit polyclonal ...read more

Product Details

Summary
Reactivity HuSpecies Glossary
Applications ELISA, IP
Clone
2B12
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated

Order Details

HUS1 Antibody (2B12) Summary

Immunogen
HUS1 (AAH07013, 1 a.a. - 280 a.a.) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. MKFRAKIVDGACLNHFTRISNMIAKLAKTCTLRISPDKLNFILCDKLANGGVSMWCELEQENFFNEFQMEGVSAENNEIYLELTSENLSRALKTAQNARALKIKLTNKHFPCLTVSVELLSMSSSSRIVTHDIPIKVIPRKLWKDLQEPVVPDPDVSIYLPVLKTMKSVVEKMKNISNHLVIEANLDGELNLKIETELVCVTTHFKDLGNPPLASESTHEDRNVEHMAEVHIDIRKLLQFLAGQQVNPTKALCNIVNNKMVHFDLLHEDVSLQYFIPALS
Specificity
HUS1 checkpoint homolog (S. pombe)
Isotype
IgG2a Kappa
Clonality
Monoclonal
Host
Mouse
Gene
HUS1
Purity
IgG purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • ELISA
  • Immunoprecipitation
Application Notes
Antibody reactivity against recombinant protein on ELISA.

Packaging, Storage & Formulations

Storage
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.4)
Preservative
No Preservative
Purity
IgG purified

Notes

Quality control test: Antibody Reactive Against Recombinant Protein.

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for HUS1 Antibody (2B12)

  • checkpoint protein HUS1
  • hHUS1
  • HUS1 (S. pombe) checkpoint homolog
  • HUS1 checkpoint homolog (S. pombe)
  • hus1+-like protein

Background

The protein encoded by this gene is a component of an evolutionarily conserved, genotoxin-activated checkpoint complex that is involved in the cell cycle arrest in response to DNA damage. This protein forms a heterotrimeric complex with checkpoint proteins RAD9 and RAD1. In response to DNA damage, the trimeric complex interacts with another protein complex consisting of checkpoint protein RAD17 and four small subunits of the replication factor C (RFC), which loads the combined complex onto the chromatin. The DNA damage induced chromatin binding has been shown to depend on the activation of the checkpoint kinase ATM, and is thought to be an early checkpoint signaling event.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol HUS1
Entrez
OMIM
Uniprot