HUS1 Products

Antibodies
HUS1 Antibody
HUS1 Antibody
NBP1-89445
Species: Hu, Mouse, Rat
Applications: WB, ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
HUS1 Antibody
HUS1 Antibody
NBP1-33589
Species: Hu, Mu, Rt
Applications: WB, IHC, IHC-P
Host: Rabbit Polyclonal
HUS1 Antibody
HUS1 Antibody
H00003364-B01P
Species: Hu
Applications: WB, ELISA, ICC/IF
Host: Mouse Polyclonal
Antibody Pairs
HUS1 Antibody Pair
HUS1 Antibody Pair
H00003364-PW2
Species: Hu
Applications: WB, IP
HUS1 Antibody Pair
HUS1 Antibody Pair
H00003364-AP11
Species: Hu
Applications: S-ELISA
HUS1 Antibody Pair
HUS1 Antibody Pair
H00003364-PW3
Species: Hu
Applications: WB, IP
Lysates
HUS1 Overexpression Lysate (D ...
HUS1 Overexpression Lysate (Denatu...
H00003364-T01
Species: Hu
Applications: WB
HUS1 Overexpression Lysate (N ...
HUS1 Overexpression Lysate (Native)
NBL1-11788
Applications: WB
Proteins
HUS1 Recombinant Protein Anti ...
HUS1 Recombinant Protein Antigen
NBP1-89445PEP
Species: Hu
Applications: AC
HUS1 Recombinant Protein
HUS1 Recombinant Protein
NBP1-50899
Applications: PAGE
RNAi
HUS1 RNAi
HUS1 RNAi
H00003364-R01
Species: Hu

Description

The protein encoded by the HUS1 gene is a component of an evolutionarily conserved, genotoxin-activated checkpoint complex that is involved in the cell cycle arrest in response to DNA damage. This protein forms a heterotrimeric complex with checkpoint proteins RAD9 and RAD1. In response to DNA damage, the trimeric complex interacts with another protein complex consisting of checkpoint protein RAD17 and four small subunits of the replication factor C (RFC), which loads the combined complex onto the chromatin. The DNA damage induced chromatin binding has been shown to depend on the activation of the checkpoint kinase ATM, and is thought to be an early checkpoint signaling event.

Bioinformatics

Entrez Human
Uniprot Human
Human
Human
Human
Product By Gene ID 3364
Alternate Names
  • hus1+-like protein
  • checkpoint protein HUS1
  • HUS1 (S. pombe) checkpoint homolog
  • hHUS1
  • HUS1 checkpoint homolog (S. pombe)

Research Areas for HUS1

Find related products by research area and learn more about each of the different research areas below.

Cell Cycle and Replication

Bioinformatics Tool for HUS1

Discover related pathways, diseases and genes to HUS1. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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