Human Total Bcl-2 DuoSet IC ELISA, 2 Plate

• Reactivity: Hu
• Applications: ELISA
• Conjugate: Biotin

Human Total Bcl-2 DuoSet IC ELISA, 2 Plate Summary

• Source: N/A
• Assay Type: Solid Phase Sandwich ELISA
• Inter-Assay: See PDF Datasheet for details
• Intra-Assay: See PDF Datasheet for details
• Spike Recovery: See PDF Datasheet for details
• Sample Volume: See PDF Datasheet for details
• Gene: BCL2

Applications/Dilutions

• Dilutions:
  • ELISA
• Application Notes: No significant interference observed with available related molecules.

Packaging, Storage & Formulations

• Storage: Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Human Total Bcl-2 DuoSet IC ELISA, 2 Plate

• apoptosis regulator Bcl-2
• B-cell CLL/lymphoma 2
• Bcl2
• Bcl-2

Background

Bcl-2 is a member of a family of proteins that regulates outer mitochondrial membrane permeability. Bcl-2 is an anti-apoptotic member that prevents release of cytochrome c from the mitochondria intermembrane space into the cytosol. Bcl-2 is present on the outer mitochondrial membrane and is also found on other membranes in some cell types. Natural Bcl-2 contains a carboxyl-terminal mitochondria targeting sequence.

Publications for Bcl-2 (DYC827B-2)(9)

Publications using DYC827B-2

• MA Almayouf, MF El-Khadrag, MA Awad, EM Al-Olayan The Effects of Silver Nanoparticles Biosynthesized Using Fig and Olive Extracts on Cutaneous leishmaniasis Induced Inflammation in Female Balb/c Mice Bioscience Reports, 2020-11-30;0(0):. 2020-11-30 [PMID: 33252120] (Mouse)
• HQ Li, JJ Fan, XH Li, D Bao MiR-507 inhibits the growth and invasion of trophoblasts by targeting CAMK4 Eur Rev Med Pharmacol Sci, 2020-06-01;24(11):5856-5862. 2020-06-01 [PMID: 32572897] (Human)
• RJ Playford, T Marchbank Pancreatic secretory trypsin inhibitor reduces multi-organ injury caused by gut ischemia/reperfusion in mice PLoS ONE, 2020-01-10;15(1):e0227059. 2020-01-10 [PMID: 31923181] (Human)
• MF El-Khadrag, EM Al-Olayan, MIY Elmallah, AM Alharbi, HM Yehia, AE Abdel Mone Probiotics and yogurt modulate oxidative stress and fibrosis in livers of Schistosoma mansoni-infected mice BMC Complement Altern Med, 2019-01-03;19(1):3. 2019-01-03 [PMID: 30606163] (Mouse)
• F He, CC Chuang, T Zhou, Q Jiang, DA Sedlock, L Zuo Redox correlation in muscle lengthening and immune response in eccentric exercise PLoS ONE, 2018-12-27;13(12):e0208799. 2018-12-27 [PMID: 30589838] (Human)
• Abdullah A, Mohammed A, Rasedee A, Mirghani M Oxidative stress-mediated apoptosis induced by ethanolic mango seed extract in cultured estrogen receptor positive breast cancer MCF-7 cells. Int J Mol Sci, 2015-02-05;16(2):3528-36. 2015-02-05 [PMID: 25664859] (Human)
• Poggi A, Prevosto C, Catellani S, Rocco I, Garuti A, Zocchi MR Engagement of CD31 delivers an activating signal that contributes to the survival of chronic lymphocytic leukaemia cells. Br. J. Haematol., 2010-08-31;151(3):252-64. 2010-08-31 [PMID: 20813004] (Human)
• Grcevic D, Kusec R, Kovacic N, Lukic A, Lukic IK, Ivcevic S, Nemet D, Seiwerth RS, Ostojic SK, Croucher PI, Marusic A Bone morphogenetic proteins and receptors are over-expressed in bone-marrow cells of multiple myeloma patients and support myeloma cells by inducing ID genes. Leuk. Res., 2009-11-18;34(6):742-51. 2009-11-18 [PMID: 19926132] (Human)
• Vucicevic L, Misirkic M, Janjetovic K, Harhaji-Trajkovic L, Prica M, Stevanovic D, Isenovic E, Sudar E, Sumarac-Dumanovic M, Micic D, Trajkovic V AMP-activated protein kinase-dependent and -independent mechanisms underlying in vitro antiglioma action of compound C. Biochem. Pharmacol., 2009-03-14;77(11):1684-93. 2009-03-14 [PMID: 19428322] (Human, Mouse, Rat)

Bioinformatics

• Gene Symbol: BCL2