Human Phospho-PDGF R alpha DuoSet IC ELISA, 2 Plate

Images

 
There are currently no images for PDGFR alpha (DYC2114-2).

Every product we sell is backed by Novus' 100% Guarantee. If you have used this product, please submit your images and reviews to earn reward points.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications ELISA
Conjugate
Biotin

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price

Human Phospho-PDGF R alpha DuoSet IC ELISA, 2 Plate Summary

Assay Type
Solid Phase Sandwich ELISA
Inter-Assay
See PDF Datasheet for details
Intra-Assay
See PDF Datasheet for details
Spike Recovery
See PDF Datasheet for details
Sample Volume
See PDF Datasheet for details
Gene
PDGFRA

Applications/Dilutions

Dilutions
  • ELISA
Application Notes
No significant interference observed with available related molecules.
Publications
Read Publications using DYC2114-2.

Packaging, Storage & Formulations

Storage
Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Human Phospho-PDGF R alpha DuoSet IC ELISA, 2 Plate

  • alpha-type platelet-derived growth factor receptor
  • CD140 antigen-like family member A
  • CD140a antigen
  • CD140a
  • EC 2.7.10
  • EC 2.7.10.1
  • MGC74795
  • PDGF R alpha
  • PDGFR alpha
  • PDGFR2
  • PDGFRA
  • PDGFRA/BCR fusion
  • PDGF-R-alpha
  • platelet-derived growth factor receptor, alpha polypeptide
  • rearranged-in-hypereosinophilia-platelet derived growth factor receptor alphafusion protein
  • RHEPDGFRA

Background

PDGF R alpha (Platelet-Derived Growth Factor Receptor alpha) is a transmembrane receptor tyrosine kinase that can form homodimers or heterodimers with PDGF R beta when engaged by dimers of the PDGF ligands. PDGF R alpha binds to PDGF-AA, PDGF-AB, and PDGF-CC. It is strongly expressed in oligodendrocyte, lung, skin, and intestinal progenitor cells, at low levels in most mesenchymal cells, and can be induced by inflammation. PDGF R alpha function is important during formation of the cranial and cardiac neural crest, retina, gonads, lung alveoli, intestinal villi, skin, hair follicles, skeleton, teeth, palate, and interstitial kidney mesenchyme. Dysregulated PDGF R alpha signaling can result in spina bifida or cleft palate-type malformations. Postnatally, PDGF R alpha is implicated in gliomas and fibrotic disorders of lung, heart, and skin (scleroderma).

Customers Who Viewed This Item Also Viewed...

AF1356
Species: Hu, Mu
Applications: CyTOF-ready, Flow, IHC, Simple Western, WB
AF1042
Species: Mu
Applications: IHC, WB
AF231
Species: Hu
Applications: CyTOF-ready, ELISA(Cap), ELISA(Det), ELISA(Sta), Flow, ICC, IHC, IP, Simple Western, WB
NB600-1071
Species: Hu(-), Mu
Applications: ELISA, Flow, ICC/IF, IHC, IHC-Fr, IHC-P, IP, WB
221-AA
Species: Hu
Applications: BA
NB200-103
Species: Hu, Mu, Rt, Xp(-), Ye
Applications: CyTOF-ready, ELISA, Flow-IC, Flow, ICC/IF, IHC, IHC-Fr, IHC-P, IP, WB
NB200-106
Species: Mu, Rt
Applications: ELISA, ICC/IF, IHC, IHC-Fr, IHC-P, WB
AF644
Species: Mu
Applications: CyTOF-ready, Flow, IHC, Neut, WB
255-SC/CF
Species: Hu
Applications: BA
NB600-1287
Species: Ca, Hu, Mu, Rb, Rt
Applications: CyTOF-ready, Flow, ICC/IF, IHC, IHC-P, IP, WB
NBP2-46527
Species: Hu, Mu, Rt
Applications: IHC, IHC-P
NBP1-85064
Species: Hu
Applications: ICC/IF, IHC, IHC-P, WB
AF887
Species: Hu, Mu, Rt
Applications: CyTOF-ready, IHC, ICFlow, Simple Western, WB
AF3844
Species: Hu, Mu
Applications: IHC
DVE00
Species: Hu
Applications: ELISA
1687-CC/CF
Species: Hu
Applications: BA
AF5414
Species: Hu
Applications: Simple Western, WB
NB300-223
Species: Bv, Ca, Ch, Eq, Hu, Mu, Po, Rt
Applications: ICC/IF, IHC, IHC-Fr, IHC-P, WB

Publications for PDGFR alpha (DYC2114-2)(7)

We have publications tested in 2 confirmed species: Human, Porcine.


Filter By Application
All Applications
Filter By Species
Human
(6)
Porcine
(1)
All Species
Showing Publications 1 - 7 of 7.
Publications using DYC2114-2 Applications Species
Uezumi A, Fukada S, Yamamoto N, Ikemoto-Uezumi M, Nakatani M, Morita M, Yamaguchi A, Yamada H, Nishino I, Hamada Y, Tsuchida K Identification and characterization of PDGFRalpha+ mesenchymal progenitors in human skeletal muscle. Cell Death Dis, 2014;5(0):e1186. 2014 [PMID: 24743741] (Human) Human
Wollin L, Maillet I, Quesniaux V, Holweg A, Ryffel B Antifibrotic and anti-inflammatory activity of the tyrosine kinase inhibitor nintedanib in experimental models of lung fibrosis. J Pharmacol Exp Ther, 2014;349(2):209-20. 2014 [PMID: 24556663] (Human) Human
Pellet-Many C, Frankel P, Evans IM, Herzog B, Junemann-Ramirez M, Zachary IC Neuropilin-1 mediates PDGF stimulation of vascular smooth muscle cell migration and signalling via p130Cas. Biochem. J., 2011;435(3):609-18. 2011 [PMID: 21306301] (Human) Human
Schultz JD, Rotunno S, Riedel F, Anders C, Erben P, Hofheinz RD, Faber A, Thorn C, Sommer JU, Hormann K, Sauter A Synergistic effects of imatinib and carboplatin on VEGF, PDGF and PDGF-Ralpha/beta expression in squamous cell carcinoma of the head and neck in vitro. Int. J. Oncol., 2011;38(4):1001-12. 2011 [PMID: 21249316] (Human) Human
Loizos N, Lariccia L, Weiner J, Griffith H, Boin F, Hummers L, Wigley F, Kussie P Lack of detection of agonist activity by antibodies to platelet-derived growth factor receptor alpha in a subset of normal and systemic sclerosis patient sera. Arthritis Rheum., 2009;60(4):1145-51. 2009 [PMID: 19333919] (Porcine) Porcine
Soroceanu L, Akhavan A, Cobbs CS Platelet-derived growth factor-alpha receptor activation is required for human cytomegalovirus infection. Nature, 2008;455(7211):391-5. 2008 [PMID: 18701889] (Human) Human
Ball SG, Shuttleworth CA, Kielty CM Vascular endothelial growth factor can signal through platelet-derived growth factor receptors. J. Cell Biol., 2007;177(3):489-500. 2007 [PMID: 17470632] (Human) Human

Reviews for PDGFR alpha (DYC2114-2) (0)

There are no reviews for PDGFR alpha (DYC2114-2). By submitting a review you will receive an Amazon e-Gift Card or Novus Product Discount.
  • Review with no image -- $10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen
  • Review with an image -- $25/€18/£15/$25 CAD/¥150 Yuan/¥2500 Yen

Product General Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

FAQs for PDGFR alpha (DYC2114-2) (0)

There are no specific FAQs related to this product. Read our general customer & technical service FAQs.

Additional PDGFR alpha Products

Bioinformatics Tool for PDGFR alpha (DYC2114-2)

Discover related pathways, diseases and genes to PDGFR alpha (DYC2114-2). Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
Visit Tool

Diseases for PDGFR alpha (DYC2114-2)

Discover more about diseases related to PDGFR alpha (DYC2114-2).
 

Pathways for PDGFR alpha (DYC2114-2)

View related products by pathway.

PTMs for PDGFR alpha (DYC2114-2)

Learn more about PTMs related to PDGFR alpha (DYC2114-2).

Blogs on PDGFR alpha

There are no specific blogs for PDGFR alpha, but you can read our latest blog posts.

Customers Who Bought This Also Bought

Contact Information

Product PDFs

Review this Product

Be the first to review our Human Phospho-PDGF R alpha DuoSet IC ELISA, 2 Plate and receive a gift card or discount.

Bioinformatics

Gene Symbol PDGFRA