Human NT-4 DuoSet ELISA, 15 Plate

• Reactivity: Hu
• Applications: ELISA
• Conjugate: Biotin

Human NT-4 DuoSet ELISA, 15 Plate Summary

• Source: N/A
• Assay Type: Solid Phase Sandwich ELISA
• Inter-Assay: See PDF Datasheet for details
• Intra-Assay: See PDF Datasheet for details
• Spike Recovery: See PDF Datasheet for details
• Sample Volume: See PDF Datasheet for details
• Gene: NTF4

Applications/Dilutions

• Dilutions:
  • ELISA
• Application Notes: No significant interference observed with available related molecules.

Packaging, Storage & Formulations

• Storage: Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Human NT-4 DuoSet ELISA, 15 Plate

• GLC10
• GLC1O
• neurotrophic factor 4
• neurotrophic factor 5
• neurotrophin 4
• neurotrophin 5 (neurotrophin 4/5)
• neurotrophin-4
• neurotrophin-5
• Neutrophic factor 4
• NT4
• NT-4
• NT-4/5
• NT-5
• NTF4
• NTF5
• NTF5NT5

Background

Neurotrophin-3 (NT-3) and Neurotrophin-4 (NT-4) are members of the NGF family of neurotrophic factors that are required for the differentiation and survival of specific neuronal subpopulations. The neurotrophin family is comprised of at least four proteins including NGF, BDNF, NT-3, and NT-4/5. These secreted cytokines are synthesized as prepropeptides that are proteolytically processed to generate active propeptides and mature protein homodimers. Mature NT-4 also forms heterodimers with BDNF or NT-3. Neurotrophins induce dimerization and activation of Trk family receptors and promote the development and survival of selected peripheral and CNS neurons. All neurotrophins have six conserved disulfide-linked cysteine residues.

Publications for NT-4 (DY268)(7)

Publications using DY268

• D?bkowska, M;Kosiorowska, A;Machali?ski, B; The Impact of Serum Protein Adsorption on PEGylated NT3-BDNF Nanoparticles-Distribution, Protein Release, and Cytotoxicity in a Human Retinal Pigmented Epithelial Cell Model Pharmaceutics 2023-08-30 [PMID: 37765206] (Human)
• M D?bkowska, D Rogi?ska, P K?os, A Sobu?, M Adamczak, Z Litwi?ska, A Machali?sk, B Machali?sk Electrostatic complex of neurotrophin 4 with dendrimer nanoparticles: controlled release of protein in vitro and in vivo Int J Nanomedicine, 2019-08-01;14(0):6117-6131. 2019-08-01 [PMID: 31534337] (Human, Mouse)
• YR Kim, SM Ahn, ME Pak, HJ Lee, DH Jung, YI Shin, HK Shin, BT Choi Potential benefits of mesenchymal stem cells and electroacupuncture on the trophic factors associated with neurogenesis in mice with ischemic stroke Sci Rep, 2018-02-01;8(1):2044. 2018-02-01 [PMID: 29391466] (Mouse)
• Cynthia Azeredo Cordeiro Serum levels of neurotrophic factors in active toxoplasmic retinochoroiditis Braz J Infect Dis, 2016-12-05;0(0):. 2016-12-05 [PMID: 27932287] (Human)
• Jones JL, Anderson JM, Phuah CL, Fox EJ, Selmaj K, Margolin D, Lake SL, Palmer J, Thompson SJ, Wilkins A, Webber DJ, Compston DA, Coles AJ Improvement in disability after alemtuzumab treatment of multiple sclerosis is associated with neuroprotective autoimmunity. Brain, 2010-07-21;133(0):2232-47. 2010-07-21 [PMID: 20659956] (Human)
• Samah B, Porcheray F, Gras G Neurotrophins modulate monocyte chemotaxis without affecting macrophage function. Clin. Exp. Immunol., 2008-01-08;151(3):476-86. 2008-01-08 [PMID: 18190610] (Human)
• Kawamura K, Kawamura N, Fukuda J, Kumagai J, Hsueh AJ, Tanaka T Regulation of preimplantation embryo development by brain-derived neurotrophic factor. Dev. Biol., 2007-08-21;311(1):147-58. 2007-08-21 [PMID: 17880937] (Mouse)

FAQs for NT-4 (DY268). (Showing 1 - 1 of 1 FAQs).

1. wondering what the difference is between your quantikine and duo set elisas?
   • Usually the duosets do not have the entire kit such as plates and buffers, whereas the other kits are complete.

Bioinformatics

• Gene Symbol: NTF4