Human Neutrophil Elastase/ELA2 DuoSet ELISA, 5 Plate



Product Details

Reactivity HuSpecies Glossary
Applications ELISA

Order Details

Human Neutrophil Elastase/ELA2 DuoSet ELISA, 5 Plate Summary

Assay Type
Solid Phase Sandwich ELISA
See PDF Datasheet for details
See PDF Datasheet for details
Spike Recovery
See PDF Datasheet for details
Sample Volume
See PDF Datasheet for details


Application Notes
No significant interference observed with available related molecules.
Read Publications using DY9167-05.

Packaging, Storage & Formulations

Store the unopened product at 2 - 8 °C. Do not use past expiration date.


This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Human Neutrophil Elastase/ELA2 DuoSet ELISA, 5 Plate

  • Bone marrow serine protease
  • EC 3.4.21
  • EC
  • ELA2
  • ELA2granulocyte-derived elastase
  • elastase 2, neutrophil
  • elastase, neutrophil expressed
  • Elastase-2
  • GE
  • HLEelastase-2
  • HNE
  • Human leukocyte elastase
  • Leukocyte Elastase
  • Medullasin
  • NE
  • Neutrophil Elastase
  • PMN elastase
  • PMN-E
  • polymorphonuclear elastase
  • SCN1


Neutrophil Elastase (ELA2), also known as polymorphonuclear leukocyte elastase, is a serine protease belonging to the chymotrypsin family. Located primarily in the azurophil granules of polymorphonuclear leukocytes, ELA2 function results in the degradation of many extracellular matrix macromolecules. Alpha-1 Antitrypsin (Serpin A1) and secretory leukocyte protease inhibitor (SLPI) have been shown to inhibit ELA2 activity. ELA2 may be involved in lung emphysema, cystic fibrosis, the adult respiratory distress syndrome (ARDS), rheumatoid arthritis, tumor invasion and infectious diseases.

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Publications for Neutrophil Elastase/ELA2 (DY9167-05)(14)

We have publications tested in 1 confirmed species: Human.

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Showing Publications 1 - 10 of 14. Show All 14 Publications.
Publications using DY9167-05 Applications Species
M Blanter, M Cockx, L Wittebols, S Abouelasra, M De Bondt, N Berghmans, N Pörtner, L Vanbrabant, N Lorent, M Gouwy, M Boon, S Struyf Sputum from patients with primary ciliary dyskinesia contains high numbers of dysfunctional neutrophils and inhibits efferocytosis Respiratory Research, 2022-12-17;23(1):359. 2022-12-17 [PMID: 36528664] (Human) Human
L Morimont, M Dechamps, C David, C Bouvy, C Gillot, H Haguet, J Favresse, L Ronvaux, J Candiracci, M Herzog, PF Laterre, J De Poorter, S Horman, C Beauloye, J Douxfils NETosis and Nucleosome Biomarkers in Septic Shock and Critical COVID-19 Patients: An Observational Study Biomolecules, 2022-07-27;12(8):. 2022-07-27 [PMID: 36008932] (Human) Human
SA Maskarinec, M McKelvy, K Boyle, H Hotchkiss, ME Duarte, B Addison, N Amato, S Khandelwal, GM Arepally, GM Lee Neutrophil functional heterogeneity is a fixed phenotype and is associated with distinct gene expression profiles Journal of leukocyte biology, 2022-08-02;0(0):. 2022-08-02 [PMID: 35916035] (Human) Human
MA Wesdorp, A Schwab, EI Bektas, R Narcisi, D Eglin, MJ Stoddart, GJVM Van Osch, M D'Este A culture model to analyze the acute biomaterial-dependent reaction of human primary neutrophils in vitro Oncogene, 2022-07-02;20(0):627-637. 2022-07-02 [PMID: 35846845] (Human) Human
VB Pacheco, G Nery, LL Fernandes, TV Santana, M Jimenez, L Borges, E Hatanaka, P Braga, FR Monteiro, JB Amaral, LS Alves, ALL Bachi, SG da Silva, A Birbrair, D Heller Salivary Proteome, Inflammatory, and NETosis Biomarkers in Older Adult Practitioners and Nonpractitioners of Physical Exercise Oxidative Medicine and Cellular Longevity, 2022-04-23;2022(0):3725056. 2022-04-23 [PMID: 35502212] (Human) Human
KC Ngamsri, RA Putri, C Jans, K Schindler, A Fuhr, Y Zhang, J Gamper-Tsi, S Ehnert, FM Konrad CXCR4 and CXCR7 Inhibition Ameliorates the Formation of Platelet-Neutrophil Complexes and Neutrophil Extracellular Traps through Adora2b Signaling International Journal of Molecular Sciences, 2021-12-17;22(24):. 2021-12-17 [PMID: 34948374] (Human) Human
S Cambier, M Metzemaeke, AC Carvalho, A Nooyens, C Jacobs, L Vanderbeke, B Malengier-, M Gouwy, E Heylen, P Meersseman, G Hermans, E Wauters, A Wilmer, C Consortium, D Schols, P Matthys, G Opdenakker, RE Marques, J Wauters, J Vandooren, P Proost Atypical response to bacterial co-infection and persistent neutrophilic broncho-alveolar inflammation distinguish critical COVID-19 from influenza JCI Insight, 2022-01-11;0(0):. 2022-01-11 [PMID: 34793331] (Human) Human
J Huckriede, SB Anderberg, A Morales, F de Vries, M Hultström, A Bergqvist, JT Ortiz-Pére, JW Sels, K Wichapong, M Lipcsey, M van de Pol, A Larsson, T Luther, C Reutelings, PG de Frutos, R Frithiof, GAF Nicolaes Evolution of NETosis markers and DAMPs have prognostic value in critically ill COVID-19 patients Scientific Reports, 2021-08-03;11(1):15701. 2021-08-03 [PMID: 34344929] (Human) Human
C Thomas, H Nothaft, R Yadav, C Fodor, A Alemka, O Oni, M Bell, B Rada, CM Szymanski Characterization of ecotin homologs from Campylobacter rectus and Campylobacter showae PLoS ONE, 2020-12-30;15(12):e0244031. 2020-12-30 [PMID: 33378351] (Human) Human
SJCFM Moorlag, YA Rodriguez-, J Gillard, S Fanucchi, K Theunissen, B Novakovic, CM de Bont, Y Negishi, ET Fok, L Kalafati, P Verginis, VP Mourits, VACM Koeken, LCJ de Bree, GJM Pruijn, C Fenwick, R van Crevel, LAB Joosten, I Joosten, H Koenen, MM Mhlanga, DA Diavatopou, T Chavakis, MG Netea BCG Vaccination Induces Long-Term Functional Reprogramming of Human Neutrophils Cell Rep, 2020-11-17;33(7):108387. 2020-11-17 [PMID: 33207187] (Human) Human
Show All 14 Publications.

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