Human MIS/AMH DuoSet ELISA, 15 Plate

• Reactivity: Hu
• Applications: ELISA
• Conjugate: Biotin

Human MIS/AMH DuoSet ELISA, 15 Plate Summary

• Source: N/A
• Assay Type: Solid Phase Sandwich ELISA
• Inter-Assay: See PDF Datasheet for details
• Intra-Assay: See PDF Datasheet for details
• Spike Recovery: See PDF Datasheet for details
• Sample Volume: See PDF Datasheet for details
• Gene: AMH

Applications/Dilutions

• Dilutions:
  • ELISA
• Application Notes: No significant interference observed with available related molecules.

Packaging, Storage & Formulations

• Storage: Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Human MIS/AMH DuoSet ELISA, 15 Plate

• AMH
• MIF
• MIS
• Muellerian hormone
• muellerian-inhibiting factor
• muellerian-inhibiting substance
• Mullerian hormone
• Mullerian inhibiting factor
• Mullerian inhibiting substance

Background

Müllerian inhibiting substance (MIS), also named anti-Müllerian hormone (AMH), is a tissue-specific TGF-beta superfamily growth factor. Its expression is restricted to Sertoli cells of fetal and postnatal testis, and to granulosa cells of postnatal ovary. MIS is synthesized and secreted as a disulfide-linked homodimeric propeptide. Proteolytic cleavage is required to separate the N-terminal proregion from the C-terminal bioactive peptide. Both fragments remain associated in a non-covalent complex. The C-terminal sequence forms a cysteine knot via seven canonical cysteine residues found in TGF-beta superfamily members.

Publications for MIS/AMH (DY1737)(4)

Publications using DY1737

• Xie, J;Yang, Y;Zhuo, A;Gao, M;Tang, L;Xiao, Y;Zhu, H;Fu, X; Exosomes derived from mesenchymal stem cells attenuate NLRP3-related pyroptosis in autoimmune premature ovarian insufficiency via the NF-?B pathway Reproductive biomedicine online 2024-01-09 [PMID: 38569224] (Human, Mouse)
• Buckenmeyer, MJ;Sukhwani, M;Iftikhar, A;Nolfi, AL;Xian, Z;Dadi, S;Case, ZW;Steimer, SR;D'Amore, A;Orwig, KE;Brown, BN; A bioengineered in situ ovary (ISO) supports follicle engraftment and live-births post-chemotherapy Journal of tissue engineering 2023-11-17 [PMID: 38029018] (Porcine)
• L Cook, M Sengelmann, B Winkler, C Nagl, S Koch, U Schlomann, EP Slater, MA Miller, EP von Strand, B Dörsam, C Preu beta er, JW Bartsch ADAM8-Dependent Extracellular Signaling in the Tumor Microenvironment Involves Regulated Release of Lipocalin 2 and MMP-9 International Journal of Molecular Sciences, 2022-02-10;23(4):. 2022-02-10 [PMID: 35216088] (Human)
• E Merlini, C Tincati, V Sacchi, M Augello, V Bono, ES Cannizzo, M Allegrini, L Gazzola, AD Monforte, AM Marconi, M Ravizza, G Marchetti Predictors of low ovarian reserve in cART-treated women living with HIV Medicine, 2021-10-01;100(39):e27157. 2021-10-01 [PMID: 34596114] (Human)

FAQs for MIS/AMH (DY1737). (Showing 1 - 1 of 1 FAQs).

1. What is the difference between the Quantikine and Duoset ELISA kits?
   • Our Quantikine kits are fully optimized and validated for the sample types listed on the product specific webpage and datasheet, as this can vary between kits. Each kit is supplied ready to use with one pre-coated 96-well plate, a detection antibody directly conjugated to HRP, and all other necessary reagents. These kits are ideal for researchers who want the convenience of a ready to use and optimized ELISA product. Some of these kits are also available prepackaged in larger 6 and 50 plate sizes.Our DuoSet Kits, in contrast, are ELISA development kits containing the capture and detection antibody, the mass-value calibrated standard, and streptavidin-HRP to prepare approximately 5 or 15 plates. Ancillary reagents will need to be used/purchased, and for most kits, we will recommend one of our Ancillary Reagent Kits, which contain the reagents we use ourselves in-house. DuoSet kits are validated only for cell culture supernatant samples and therefore require further development and validation for accurate measurement in more complex samples such as serum and plasma. Our DuoSet Kits offer an economical, flexible alternative for the experienced ELISA user.

Bioinformatics

• Gene Symbol: AMH