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Human L-Selectin/CD62L DuoSet ELISA, 15 Plate

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications ELISA
Conjugate
Biotin

Order Details

Human L-Selectin/CD62L DuoSet ELISA, 15 Plate Summary

Assay Type
Solid Phase Sandwich ELISA
Inter-Assay
See PDF Datasheet for details
Intra-Assay
See PDF Datasheet for details
Spike Recovery
See PDF Datasheet for details
Sample Volume
See PDF Datasheet for details
Gene
SELL

Applications/Dilutions

Dilutions
  • ELISA
Application Notes
No significant interference observed with available related molecules.
Publications
Read Publications using DY728.

Packaging, Storage & Formulations

Storage
Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Human L-Selectin/CD62L DuoSet ELISA, 15 Plate

  • CD62L antigen
  • CD62L
  • gp90-MEL
  • hLHRc
  • LAM1
  • LAM-1
  • LAM1LECAM1
  • LECAM1
  • LEU8
  • Leu-8
  • Leukocyte adhesion molecule 1
  • Leukocyte surface antigen Leu-8
  • Leukocyte-endothelial cell adhesion molecule 1
  • LNHR
  • LNHRTQ1
  • LSEL
  • L-Selectin
  • LYAM1
  • Lyam-1
  • LYAM1CD62 antigen-like family member L
  • Lymph node homing receptor
  • lymphocyte adhesion molecule 1
  • pln homing receptor
  • PLNHR
  • selectin L
  • SELL
  • TQ1

Background

The Selectin family is comprised of three members, E-Selectin, L-Selectin, and P-Selectin. E-Selectin [endothelial leukocyte adhesion molecule-1 (ELAM-1), CD62E] is transiently expressed on vascular endothelial cells in response to IL-1 beta and TNF-alpha. The human and rat proteins share approximately 67% amino acid sequence identity. The mouse and rat proteins share approximately 78% amino acid sequence identity. L-Selectin (Leukocyte Selectin, LAM-1, LECAM-1, LECCAM-1, TQ1, Leu-8, MEL-14 antigen, DREG, lymph node homing receptor, CD62L) is expressed constitutively on a wide variety of leukocytes. Two forms of L-Selectin have been reported, apparently arising as a result of post-translational modifications. Human and mouse L-Selectin share 76% amino acid sequence identity. Human P-Selectin (GMP-140, LECAM-3, PADGEM, CD62P) is expressed by activated platelets and endothelial cells. The extracellular domains of human and mouse P-Selectin share approximately 73% amino acid sequence identity.

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Publications for L-Selectin/CD62L (DY728)(7)

We have publications tested in 2 confirmed species: Human, Chinese Hamster.


Filter By Application
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Human
(6)
Chinese Hamster
(1)
All Species
Showing Publications 1 - 7 of 7.
Publications using DY728 Applications Species
J Segura, J Ireland, Z Zou, G Roth, J Buchwald, TJ Shen, E Fischer, S Moir, TW Chun, PD Sun HIV-1 release requires Nef-induced caspase activation PLoS ONE, 2023-02-13;18(2):e0281087. 2023-02-13 [PMID: 36780482] (Human) Human
HK Drescher, A Schippers, S Rosenhain, F Gremse, L Bongiovann, A Bruin, S Eswaran, SU Gallage, D Pfister, M Szydlowska, M Heikenwald, S Weiskirche, N Wagner, C Trautwein, R Weiskirche, DC Kroy L-Selectin/CD62L is a Key Driver of Non-Alcoholic Steatohepatitis in Mice and Men Cells, 2020-04-29;9(5):. 2020-04-29 [PMID: 32365632] (Human) Human
AA Arguinano, NC Ndiaye, C Masson, S Visvikis-S Pleiotropy of ABO gene: correlation of rs644234 with E-selectin and lipid levels Clin. Chem. Lab. Med., 2018-04-25;0(0):. 2018-04-25 [PMID: 29373315] (Human) Human
M Spencer, N Max, J Ireland, Z Zou, R Wang, P Sun Over-expression of a human CD62L ecto-domain and a potential role of RNA pseudoknot structures in recombinant protein expression Protein Expr. Purif., 2017-08-24;140(0):65-73. 2017-08-24 [PMID: 28842197] (Chinese Hamster) Chinese Hamster
AA Aldasoro A, S Dadé, M Stathopoul, M Derive, N Coumba Ndi, T Xie, C Masson, S Gibot, S Visvikis-S TREM-1 SNP rs2234246 regulates TREM-1 protein and mRNA levels and is associated with plasma levels of L-selectin PLoS ONE, 2017-08-03;12(8):e0182226. 2017-08-03 [PMID: 28771614] (Human) Human
PL Chiang, HL Chen, CH Lu, PC Chen, MH Chen, IH Yang, NW Tsai, WC Lin White matter damage and systemic inflammation in Parkinson's disease BMC Neurosci, 2017-06-08;18(1):48. 2017-06-08 [PMID: 28595572] (Human) Human
Chang , Elizabet, Eckert , Mark A, Ali , M Monsur, Riazifar , Hamidrez, Pone , Egest J, Liu , Linan, Zhao , Weian Facile supermolecular aptamer inhibitors of L-selectin. PLoS ONE, 2015-03-31;10(3):e0123034. 2015-03-31 [PMID: 25826688] (Human) Human

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Additional L-Selectin/CD62L Products

Blogs on L-Selectin/CD62L.

L-selectin (CD62L antigen, Leukocyte surface antigen Leu-8)
L-selectin is a member of the selectin family of glycoprotein adhesion and homing receptors that recognize sialyated carbohydrate groups and regulate lymphocyte-endothelial cell interactions. It is a type I transmembrane cell adhesion molecule (CAM) a...  Read full blog post.

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Bioinformatics

Gene Symbol SELL