Human IL-7 Quantikine HS ELISA Kit

Product Details

Summary
Reactivity HuSpecies Glossary
Applications ELISA
Conjugate
HRP

Order Details

Human IL-7 Quantikine HS ELISA Kit Summary

Background
The Quantikine HS Human IL-7 Immunoassay is a solid phase ELISA that specifically measures IL-7 in 18-24 hours (with an overnight incubation step). This kit is designed to measure IL-7 levels in cell culture supernates, serum, and plasma. It contains E. coli-expressed recombinant human IL-7 and antibodies raised against the recombinant factor. It has been shown to quantitate the rec...ombinant factor accurately. Results obtained using natural IL-7 showed linear curves that were parallel to the standard curves obtained using the kit standards. These results indicate that this kit can be used to determine relative mass values for natural human IL-7.
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Specificity
Natural and recombinant human IL-7
Assay Type
Solid Phase Sandwich ELISA
Inter-Assay
See PDF Datasheet for details
Intra-Assay
See PDF Datasheet for details
Spike Recovery
See PDF Datasheet for details
Sample Volume
See PDF Datasheet for details
Gene
IL7

Applications/Dilutions

Dilutions
  • ELISA
Application Notes
No significant interference observed with available related molecules.
Publications
Read Publications using HS750.

Packaging, Storage & Formulations

Storage
Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Human IL-7 Quantikine HS ELISA Kit

  • IL7
  • IL-7
  • IL-7interleukin-7
  • interleukin 7
  • Lymphopoietin-1
  • PBGF

Background

IL-7 (Interleukin-7) is a cytokine that plays important roles in lymphocyte differentiation, proliferation, and survival. IL-7 is produced by stromal epithelial cells of the thymus, bone marrow, and intestines. It signals through a receptor complex composed of IL-7 R alpha/CD127 and the Common gamma Chain. gamma c is also a subunit of the receptors for IL-2, -4, -9, -15, and -21. IL-7 contributes to the maintenance of all naïve and memory T cells. It is required for optimal T cell-dendritic cell interaction. In mouse, IL-7 activation of IL-7 R alpha is critical for both T cell and B cell lineage development, while in humans, it is required for T cell but not for B cell development.

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Publications for IL-7 (HS750)(41)

We have publications tested in 6 confirmed species: Human, Primate, Primate - Cebus capucinus (White-headed Capuchin Monkey), Primate - Macaca fascicularis (Crab-eating Monkey or Cynomolgus Macaque), Primate - Macaca mulatta (Rhesus Macaque), Primate - Papio cynocephalus (Yellow Baboon).


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Human
(34)
Primate
(1)
Primate - Cebus capucinus (White-headed Capuchin Monkey)
(1)
Primate - Macaca fascicularis (Crab-eating Monkey or Cynomolgus Macaque)
(1)
Primate - Macaca mulatta (Rhesus Macaque)
(2)
Primate - Papio cynocephalus (Yellow Baboon)
(1)
All Species
Showing Publications 1 - 10 of 41. Show All 41 Publications.
Publications using HS750 Applications Species
T Sainz, L Diaz, D Rojo, MI Clemente, C Barbas, MJ Gosalbes, N Jimenez-He, L Escosa, S Guillen, JT Ramos, MÁ Muñoz-Fern, ML Navarro, MJ Mellado, S Serrano-Vi Targeting the Gut Microbiota of Vertically HIV-Infected Children to Decrease Inflammation and Immunoactivation: A Pilot Clinical Trial Nutrients, 2022;14(5):. 2022 [PMID: 35267967] (Human) Human
C Bacchus-So, M Fitch, J Symons, M Abdel-Mohs, DB Reeves, R Hoh, M Stone, J Hiatt, P Kim, A Chopra, H Ahn, VA York, DL Cameron, FM Hecht, JN Martin, SA Yukl, S Mallal, PU Cameron, SG Deeks, JT Schiffer, SR Lewin, MK Hellerstei, JM McCune, PW Hunt Relationship between CD4 T cell turnover, cellular differentiation and HIV persistence during ART PloS Pathogens, 2021;17(1):e1009214. 2021 [PMID: 33465157] (Human) Human
J Xun, T Qi, L Zou, Q Tang, Y Shen, J Yang, L Xie, Y Ji, R Zhang, L Liu, J Wang, C Steinhart, Z Wang, Y Tang, W Song, J Sun, J Cheng, X Le, H Wu, X He, R Chen, J Chen, H Lu Mycobacterium tuberculosis co-infection is associated with increased surrogate marker of the HIV reservoir AIDS Res Ther, 2020;17(1):63. 2020 [PMID: 33076959] (Human) Human
Y Yuan, C Zhou, Q Yang, S Ma, X Wang, X Guo, Y Ding, J Tang, Y Zeng, D Li HIV-1 Tat protein inhibits the hematopoietic support function of human bone marrow mesenchymal stem cells Virus Res., 2019;273(0):197756. 2019 [PMID: 31521762] (Human) Human
A Rajamanick, S Munisankar, Y Bhootra, CK Dolla, K Thiruvenga, TB Nutman, S Babu Altered levels of memory T cell subsets and common ?c cytokines in Strongyloides stercoralis infection and partial reversal following anthelmintic treatment PLoS Negl Trop Dis, 2018;12(5):e0006481. 2018 [PMID: 29795573] (Human) Human
J Seyfarth, C Lundtoft, K Förtsch, H Ahlert, J Rosenbauer, C Baechle, M Roden, RW Holl, E Mayatepek, S Kummer, T Meissner, M Jacobsen IL7RA haplotypes differentially affect soluble IL-7 receptor and IL-7 serum concentrations in children with type 1 diabetes Pediatr Diabetes, 2018;0(0):. 2018 [PMID: 29484785] (Human) Human
C Lundtoft, A Afum-Adjei, J Rimpler, K Harling, N Nausch, M Kohns, E Adankwah, F Lang, L Olbrich, E Mayatepek, E Owusu-Dabo, M Jacobsen Aberrant plasma IL-7 and soluble IL-7 receptor levels indicate impaired T-cell response to IL-7 in human tuberculosis PLoS Pathog., 2017;13(6):e1006425. 2017 [PMID: 28582466] (Human) Human
R Ponte, M Rancez, S Figueiredo, J Dutrieux, V Fabre-Mers, B Charmeteau, T Guilbert, JP Routy, R Cheynier, A Couëdel-Co Acute Simian Immunodeficiency Virus Infection Triggers Early and Transient Interleukin-7 Production in the Gut, Leading to Enhanced Local Chemokine Expression and Intestinal Immune Cell Homing Front Immunol, 2017;8(0):588. 2017 [PMID: 28579989] (Primate) Primate
NP Kumar, VV Banurekha, D Nair, S Babu Diminished plasma levels of common ?-chain cytokines in pulmonary tuberculosis and reversal following treatment PLoS ONE, 2017;12(4):e0176495. 2017 [PMID: 28448542] (Human) Human
P Severino, DT Palomino, H Alvarenga, CB Almeida, DC Pasqualim, A Cury, PR Salvalaggi, AL De Vasconc, MC Andrade, T Aloia, S Bromberg, LV Rizzo, FA Rocha, LC Marti Human Lymph Node-Derived Fibroblastic and Double-Negative Reticular Cells Alter Their Chemokines and Cytokines Expression Profile Following Inflammatory Stimuli Front Immunol, 2017;8(0):141. 2017 [PMID: 28261205] (Human) Human
Show All 41 Publications.

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Bioinformatics

Gene Symbol IL7