Human IL-7 DuoSet ELISA, 15 Plate

• Reactivity: Hu
• Applications: ELISA
• Conjugate: Biotin

Human IL-7 DuoSet ELISA, 15 Plate Summary

• Source: N/A
• Assay Type: Solid Phase Sandwich ELISA
• Inter-Assay: See PDF Datasheet for details
• Intra-Assay: See PDF Datasheet for details
• Spike Recovery: See PDF Datasheet for details
• Sample Volume: See PDF Datasheet for details
• Gene: IL7

Applications/Dilutions

• Dilutions:
  • ELISA
• Application Notes: No significant interference observed with available related molecules.

Packaging, Storage & Formulations

• Storage: Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Human IL-7 DuoSet ELISA, 15 Plate

• IL7
• IL-7
• IL-7interleukin-7
• interleukin 7
• Lymphopoietin-1
• PBGF

Background

IL-7 (Interleukin-7) is a cytokine that plays important roles in lymphocyte differentiation, proliferation, and survival. IL-7 is produced by stromal epithelial cells of the thymus, bone marrow, and intestines. It signals through a receptor complex composed of IL-7 R alpha/CD127 and the Common gamma Chain. gamma c is also a subunit of the receptors for IL-2, -4, -9, -15, and -21. IL-7 contributes to the maintenance of all naïve and memory T cells. It is required for optimal T cell-dendritic cell interaction. In mouse, IL-7 activation of IL-7 R alpha is critical for both T cell and B cell lineage development, while in humans, it is required for T cell but not for B cell development.

Publications for IL-7 (DY207)(12)

Publications using DY207

• Coughlin, CA;Chahar, D;Lekakis, M;Youssfi, AA;Li, L;Roberts, E;Gallego, NC;Volmar, CH;Landgren, O;Brothers, S;Griswold, AJ;Amador, C;Bilbao, D;Maura, F;Schatz, JH; Bruton's tyrosine kinase inhibition re-sensitizes multidrug-resistant DLBCL tumors driven by BCL10 gain-of-function mutants to venetoclax Blood cancer journal 2025-02-02 [PMID: 39894894] (Human)
• Gysan, MR;Milacek, C;Bal, C;Zech, A;Brugger, J;Milos, RI;Antoniewicz, L;Idzko, M;Gompelmann, D; Ventilatory support and inflammatory peptides in hospitalised patients with COVID-19: A prospective cohort trial PloS one 2023-11-02 [PMID: 37917760] (Human)
• LA Leroy, A Mac Donald, A Kandlur, D Bose, P Xiao, J Gagnon, F Villinger, Y Chebloune Cytokine Adjuvants IL-7 and IL-15 Improve Humoral Responses of a SHIV LentiDNA Vaccine in Animal Models Vaccines, 2022-03-17;10(3):. 2022-03-17 [PMID: 35335093] (Human)
• A Rajamanick, N Pavan Kuma, AN Pandiaraj, N Selvaraj, S Munisankar, RM Renji, V Venkataram, M Murhekar, JWV Thangaraj, SK Muthusamy, GK Chethrapil, T Bhatnagar, M Ponnaiah, S Ramasamy, S Velusamy, S Babu Characterization of memory T cell subsets and common gamma-chain cytokines in convalescent COVID-19 individuals Journal of leukocyte biology, 2022-03-08;0(0):. 2022-03-08 [PMID: 35258122] (Human)
• LGHS Aragão, JT Oliveira, JR Temerozo, MA Mendes, JA Salerno, CSG Pedrosa, T Puig-Pijua, CP Veríssimo, IM Ornelas, T Torquato, G Vitória, CQ Sacramento, N Fintelman-, S da Silva G, V Cardoso So, LRQ Souza, K Karmirian, L Goto-Silva, D Biagi, EM Cruvinel, R Dariolli, DR Furtado, PT Bozza, HL Borges, TML Souza, MZP Guimarães, SK Rehen WIN 55,212-2 shows anti-inflammatory and survival properties in human iPSC-derived cardiomyocytes infected with SARS-CoV-2 PeerJ, 2021-10-08;9(0):e12262. 2021-10-08 [PMID: 34707939] (Human)
• G Dunsmore, EP Rosero, S Shahbaz, DM Santer, J Jovel, P Lacy, S Houston, S Elahi Neutrophils promote T-cell activation through the regulated release of CD44-bound Galectin-9 from the cell surface during HIV infection PloS Biology, 2021-08-19;19(8):e3001387. 2021-08-19 [PMID: 34411088] (Human)
• GR Kathamuthu, K Moideen, R Sridhar, D Baskaran, S Babu Altered plasma levels of &betaC and &gammaC chain cytokines and post-treatment modulation in tuberculous lymphadenitis Cytokine, 2020-12-17;138(0):155405. 2020-12-17 [PMID: 33341600] (Human)
• Rao M, Vogelzang A, Kaiser P, Schuerer S, Kaufmann S, Gengenbacher M The tuberculosis vaccine candidate Bacillus Calmette-Guerin DeltaureC::hly coexpressing human interleukin-7 or -18 enhances antigen-specific T cell responses in mice. PLoS ONE, 2013-11-13;8(11):e78966. 2013-11-13 [PMID: 24236077] (Bacteria)
• Raqib R, Ahmed S, Sultana R, Wagatsuma Y, Mondal D, Hoque AM, Nermell B, Yunus M, Roy S, Persson LA, Arifeen SE, Moore S, Vahter M Effects of in utero arsenic exposure on child immunity and morbidity in rural Bangladesh. Toxicol. Lett., 2009-01-09;185(3):197-202. 2009-01-09 [PMID: 19167470] (Human)
• Hirosako S, Goto E, Fujii K, Tsumori K, Hirata N, Tsumura S, Kamohara H, Kohrogi H Human bronchial intraepithelial T cells produce interferon-gamma and stimulate epithelial cells. Clin. Exp. Immunol., 2008-11-26;155(2):266-74. 2008-11-26 [PMID: 19040600] (Human)
• Monti P, Scirpoli M, Maffi P, Ghidoli N, De Taddeo F, Bertuzzi F, Piemonti L, Falcone M, Secchi A, Bonifacio E Islet transplantation in patients with autoimmune diabetes induces homeostatic cytokines that expand autoreactive memory T cells. J. Clin. Invest., 2008-05-01;118(5):1806-14. 2008-05-01 [PMID: 18431516] (Human)
• Miranda-Carus ME, Benito-Miguel M, Llamas MA, Balsa A, Martin-Mola E Human T cells constitutively express IL-15 that promotes ex vivo T cell homeostatic proliferation through autocrine/juxtacrine loops. J. Immunol., 2005-09-15;175(6):3656-62. 2005-09-15 [PMID: 16148110] (Human)

FAQs for IL-7 (DY207). (Showing 1 - 1 of 1 FAQs).

1. wondering what the difference is between your quantikine and duo set elisas?
   • Usually the duosets do not have the entire kit such as plates and buffers, whereas the other kits are complete.

Bioinformatics

• Gene Symbol: IL7